SCHEMBL3848759

SCHEMBL3848759

Cc1sc(C=Cc2ccc(C#N)cc2)c(C)c1C1=C(c2c(C)sc3ccc(C=Cc4ccc(N(C)C)cc4)cc23)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ INSR P06213 6/20 0.34
▸ KDM4E B2RXH2 1/20 0.31
▸ APP P05067 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3848760 0.93 INSR (0.32) INSRKDM4EAPP
SCHEMBL3851312 0.84 FBP1 (0.32) KDM4E
SCHEMBL3849455 0.82 INSR (0.39) INSRAPP
SCHEMBL3871298 0.80 TUBB1 (0.37) APP
SCHEMBL3849458 0.76 INSR (0.39) INSRAPP
SCHEMBL3853710 0.75 TUBB1 (0.33) KDM4E
SCHEMBL3871299 0.72 TUBB1 (0.37) KDM4EAPP
SCHEMBL3855910 0.72 RELA (0.41) KDM4E
SCHEMBL28747182 0.71 FBP1 (0.30) —
SCHEMBL3853940 0.70 TUBB1 (0.35) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3732533-B1 SYSTEM AND METHOD FOR CUSTOMIZATION OF A PHOTOCHROMIC ARTICLE TRANSITIONS OPTICAL LTD (IE) 2025-12-10 — — EP disclosed
US-11609442-B2 System and method for customization of a photochromic article TRANSITIONS OPTICAL, LTD. (IE) 2023-03-21 — — US disclosed
US-20210055575-A1 System and Method for Customization of a Photochromic Article TRANSITIONS OPTICAL, LTD. (IE) 2021-02-25 — — US disclosed
EP-3732533-A1 SYSTEM AND METHOD FOR CUSTOMIZATION OF A PHOTOCHROMIC ARTICLE Transitions Optical, Ltd. (IE) 2020-11-04 — — EP disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 — — US disclosed
CN-1315555-C Method of alternatively dioplaying photochromic action of memory color in toy assembly, and photochromic toy having alternatively color memory PILOT INK CO LTD (JP) 2007-05-16 — — CN disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 — — US disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 — — US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 — — EP disclosed
CN-1498666-A Method of alternatively dioplaying photochromic action of memory color in toy assembly, and photochromic toy having alternatively color memory ��ī�����˹��ʽ���� 2004-05-26 — — CN disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 — — EP disclosed
Send feedback