Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GPR3 | P46089 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | AHR | P35869 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2987901 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HSD17B10GPR3ALOX5POLB | |
| SCHEMBL546371 | 0.71 | CYP1A2 (0.42) | ALDH1A1HSD17B10GPR3KDM4EAHR | |
| SCHEMBL9723837 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HSD17B10GPR3ALOX5POLB | |
| SCHEMBL650736 | 0.71 | KDM4E (0.41) | ALDH1A1HSD17B10GPR3ALOX5POLB | |
| SCHEMBL570354 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HSD17B10GPR3ALOX5POLB | |
| SCHEMBL1639050 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HSD17B10GPR3ALOX5POLB | |
| SCHEMBL2073631 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HSD17B10GPR3ALOX5POLB | |
| SCHEMBL127256 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HSD17B10GPR3ALOX5POLB | |
| SCHEMBL6709570 | 0.69 | KMT2A (0.46) | ALDH1A1HSD17B10KDM4EAHRGAA | |
| SCHEMBL718222 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HSD17B10GPR3POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102675186-B | Indol and eight-membered ring diene compound, synthetic method and application thereof in iprindole synthesis | SHANGHAI INST ORGANIC CHEM | 2014-11-12 | — | — | CN | claimed |
| CN-102675186-A | Indol and eight-membered ring diene compound, synthetic method and application thereof in iprindole synthesis | SHANGHAI INST ORGANIC CHEM | 2012-09-19 | — | — | CN | claimed |
| CN-101842353-A | 2, 3-substituted indole derivatives for treating viral infections | SCHERING CORP | 2010-09-22 | — | — | CN | disclosed |
| CN-101842374-A | 2, 3-substituted azaindole derivatives for the treatment of viral infections | SCHERING CORP | 2010-09-22 | — | — | CN | disclosed |
| CN-101821252-A | The indole derivatives and the using method thereof that replace | CHERING CORP | 2010-09-01 | — | — | CN | disclosed |
| CN-101631773-A | 4 of treatment or prevention HCV and related viral infections, the 5-ring annulated indole derivatives | SCHERING CORP | 2010-01-20 | — | — | CN | disclosed |
| CN-101611025-A | 5, the indole derivatives of 6-cyclisation and using method thereof | SCHERING CORP (US) | 2009-12-23 | — | — | CN | disclosed |
| CN-101611002-A | 4, 5-cyclized indole derivatives for the treatment or prevention of HCV and related viral infections | SCHERING CORP (US) | 2009-12-23 | — | — | CN | disclosed |
| EP-1196624-B1 | TEST MEDIA FOR IDENTIFICATION AND DIFFERENTIATION OF ENTEROBACTERIACEAE | MICROLOGY LAB L L C (US) | 2009-09-23 | — | — | EP | disclosed |
| CN-1230163-C | 2-phenyl-1- [4- (2-aminoethoxy) -benzyl ] -indole in combination with an estrogen | AMERICAN HOME PROD (US) | 2005-12-07 | — | — | CN | disclosed |
| CN-1106383-C | Estrogenic agents | AMERICAN HOME PROD (US) | 2003-04-23 | — | — | CN | disclosed |
| CN-1326347-A | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole in combination with estrogens | AMERICAN HOME PROD (US) | 2001-12-12 | — | — | CN | disclosed |
| CN-1170719-A | Estrogenic agents | AMERICAN HOME PROD (US) | 1998-01-21 | — | — | CN | disclosed |