Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232302 | 0.74 | JAK2 (0.45) | TNKS2GAAMAPTRXFP1MEN1 | |
| SCHEMBL316411 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KIF11GAAHPGD | |
| SCHEMBL2073631 | 0.71 | ALDH1A1 (0.40) | CYP1A2AHRATMALDH1A1HSD17B10 | |
| SCHEMBL1639050 | 0.71 | ALDH1A1 (0.40) | CYP1A2AHRATMALDH1A1CYP2A6 | |
| SCHEMBL127256 | 0.71 | ALDH1A1 (0.40) | AHRATMALDH1A1HSD17B10GPR3 | |
| SCHEMBL3849040 | 0.71 | ALDH1A1 (0.40) | CYP1A2AHRATMALDH1A1HSD17B10 | |
| SCHEMBL9723837 | 0.71 | ALDH1A1 (0.40) | CYP1A2AHRATMALDH1A1HSD17B10 | |
| SCHEMBL570354 | 0.71 | ALDH1A1 (0.40) | CYP1A2AHRATMALDH1A1HSD17B10 | |
| SCHEMBL650736 | 0.71 | KDM4E (0.41) | CYP1A2AHRATMALDH1A1HSD17B10 | |
| SCHEMBL2987901 | 0.71 | ALDH1A1 (0.40) | CYP1A2AHRATMALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 925 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092830-A1 | PROCESS FOR PREPARING CARBOXYL CYCLIC ACID ANHYDRIDE | PEKING UNIVERSITY (CN) | 2024-03-21 | — | — | US | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| EP-4265600-A1 | PROCESS FOR PREPARING CARBOXYL CYCLIC ACID ANHYDRIDE | Peking University (CN) | 2023-10-25 | — | — | EP | claimed |
| CN-116234546-A | GPX4 inhibitors, pharmaceutical compositions thereof and their use in the treatment of GPX4 mediated diseases | 嘉兴优博生物技术有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-115677600-A | 2, 3-dihydroquinazoline-4 (1H) -ketone derivative and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2023-02-03 | — | — | CN | claimed |
| CN-114181150-A | Pyrazole amide derivative, preparation method and application thereof | 沈阳万菱生物技术有限公司 | 2022-03-15 | — | — | CN | claimed |
| EP-3927706-A1 | IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF PROLIFERATIVE DISORDERS | 1st Biotherapeutics, Inc. (KR) | 2021-12-29 | — | — | EP | claimed |
| EP-3927705-A1 | IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | 1st Biotherapeutics, Inc. (KR) | 2021-12-29 | — | — | EP | claimed |
| US-20210347774-A1 | IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | 1ST Biotherapeutics, Inc. | 2021-11-11 | — | — | US | claimed |
| CN-113454082-A | Imidazopyridinyl compounds and their use for the treatment of neurodegenerative diseases | 第一生物治疗股份有限公司 | 2021-09-28 | — | — | CN | claimed |
| EP-0598837-A4 | AMINO ACID, ESTER AND/OR CATECHOL CONTRAST AGENTS FOR MRI. | UNIV CALIFORNIA (US) | 1994-07-13 | — | — | EP | claimed |
| EP-0598837-A1 | AMINO ACID, ESTER AND/OR CATECHOL CONTRAST AGENTS FOR MRI | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-06-01 | — | — | EP | claimed |
| WO-1993014088-A1 | ANTIHISTAMINIC PIPERAZINYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-22 | — | — | WO | claimed |
| WO-1993003351-A1 | AMINO ACID, ESTER AND/OR CATECHOL CONTRAST AGENTS FOR MRI | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-02-18 | — | — | WO | claimed |
| EP-0229947-B1 | NOVEL CRYSTALLINE SALTS OF ARYLOXY-PROPANOLAMINES, THEIR PREPARATION AND THEIR USE | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-03-13 | — | — | EP | claimed |
| EP-0391414-A2 | Benzazepine and benzothiazepine derivatives | E.R. SQUIBB & SONS, INC. (US) | 1990-10-10 | — | — | EP | claimed |
| US-4946840-A | Benzazepine and benzothiazepine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1990-08-07 | — | — | US | claimed |
| EP-0229947-A1 | Novel crystalline salts of aryloxy-propanolamines, their preparation and their use | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1987-07-29 | — | — | EP | claimed |
| US-4317832-A | ADRENERGIC BLOCKING AGENTS; HYPOTENSIVE AGENTS | KLINGLER KARL HEINZ | 1982-03-02 | — | — | US | claimed |
| US-4144340-A | ADRENERGIC BLOCKING AGENTS | DEUTSCHE GOLD UND SILBER- SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-03-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | CSNK1A1, CSNK1D, CSNK1G1 | CYP1A2 2567/4885AHR 4371/4885ATM 1296/4885 |
| US-20240092830-A1 | PROCESS FOR PREPARING CARBOXYL CYCLIC ACID ANHYDRIDE | CA9, CA7, APEH | CYP1A2 465/4885AHR 3089/4885ATM 3473/4885 |
| US-20210347774-A1 | IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | SMN1; SMN2, SNCA, HTT | CYP1A2 2916/4885AHR 813/4885ATM 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.