SCHEMBL3849644

SCHEMBL3849644

Oc1ccc(C23CC4(c5ccccc5)CC(c5ccccc5)(C2)CC(C25CC6(c7ccccc7)CC(c7ccccc7)(CC(c7ccc(O)cc7O)(C6)C2)C5)(C4)C3)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.38
ALOX5AP P20292 1/20 0.38
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
NR3C1 P04150 6/20 0.33
PGR P06401 1/20 0.33
AR P10275 1/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
TYR P14679 1/20 0.33
SIGMAR1 Q99720 2/20 0.32
OPRM1 P35372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3844976 0.88 TYR (0.35) ALOX5ESR1ESR2LMNAALOX12
SCHEMBL3759822 0.82 TYR (0.39) ALOX5ESR1ESR2LMNAALOX12
SCHEMBL3843509 0.81 AKR1B1 (0.41) ESR1ESR2MEN1KMT2A
SCHEMBL2710992 0.76 PNMT (0.46) MEN1KMT2AOPRM1
SCHEMBL3842486 0.76 CNR2 (0.34) ALOX5APMEN1GAAKMT2ALMNA
SCHEMBL3841203 0.75 LMNA (0.33) ESR1ESR2LMNAALOX12SIGMAR1
SCHEMBL3845893 0.74 CNR2 (0.38) ALOX5APESR1MEN1GAAKMT2A
SCHEMBL3842319 0.72 ESR1 (0.44) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL3843069 0.72 CNR2 (0.35) ALOX5APMEN1GAAKMT2ALMNA
SCHEMBL3759906 0.70 CNR2 (0.38) ALOX5APESR1MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed