Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.46 |
| ▸ | STAMBP | O95630 | 2/20 | 0.46 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38227 | 0.78 | HPGDS (1.00) | HPGDSSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL13876385 | 0.76 | HPGDS (0.64) | HPGDSSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL14974164 | 0.76 | HPGDS (1.00) | HPGDSSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL14974013 | 0.75 | HPGDS (1.00) | HPGDSKMT2ASIRT2MEN1 | |
| SCHEMBL38497 | 0.75 | HPGDS (1.00) | HPGDSKMT2ASIRT2MEN1 | |
| SCHEMBL5969148 | 0.74 | ESRRG (0.60) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL19654542 | 0.74 | NPC1 (0.65) | HPGDSSMN1; SMN2NPC1RAB9APSMD14 | |
| SCHEMBL14457462 | 0.73 | HPGDS (0.60) | HPGDSSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL3240913 | 0.72 | NPC1 (0.69) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL3232164 | 0.72 | ESRRG (0.59) | SMN1; SMN2NPC1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576536-A2 | HAEMATOPOIETIC-PROSTAGLANDIN D2 SYNTHASE INHIBITORS | The University of Queensland (AU) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011150457-A2 | HAEMATOPOIETIC-PROSTAGLANDIN D2 SYNTHASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2011-12-08 | — | — | WO | disclosed |