SCHEMBL19654542

SCHEMBL19654542

O=C(NCCc1cccs1)c1ccc(-c2ccc(C(=O)NCCc3cccs3)cn2)nc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.65
RAB9A P51151 9/20 0.65
SMN1; SMN2 Q16637 8/20 0.65
TAAR1 Q96RJ0 1/20 0.65
PSMD14 O00487 1/20 0.61
STAMBP O95630 1/20 0.61
COPS5 Q92905 1/20 0.61
LMNA P02545 1/20 0.61
ALDH1A1 P00352 6/20 0.59
MAPT P10636 1/20 0.59
CYP1A2 P05177 2/20 0.55
HPGDS O60760 2/20 0.54
BRD4 O60885 1/20 0.54
ROCK2 O75116 1/20 0.53
NAMPT P43490 1/20 0.51
HPGD P15428 4/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
KDM4E B2RXH2 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16496362 0.91 NPC1 (0.58) NPC1RAB9ASMN1; SMN2TAAR1PSMD14
SCHEMBL16495654 0.88 NPC1 (0.55) NPC1RAB9ASMN1; SMN2TAAR1PSMD14
SCHEMBL16495606 0.85 PSMD14 (0.56) NPC1RAB9ASMN1; SMN2TAAR1PSMD14
SCHEMBL16496007 0.85 NPC1 (0.61) NPC1RAB9ASMN1; SMN2TAAR1PSMD14
SCHEMBL16496303 0.83 TRPV1 (0.56) NPC1RAB9ASMN1; SMN2TAAR1PSMD14
SCHEMBL2653237 0.80 RAB9A (0.76) NPC1RAB9ASMN1; SMN2TAAR1PSMD14
SCHEMBL2307879 0.79 RAB9A (0.74) NPC1RAB9ASMN1; SMN2TAAR1PSMD14
SCHEMBL31396767 0.79 RAB9A (0.74) NPC1RAB9ASMN1; SMN2TAAR1PSMD14
SCHEMBL10442013 0.79 NPC1 (0.74) NPC1RAB9ASMN1; SMN2TAAR1LMNA
SCHEMBL12158613 0.79 NPC1 (1.00) NPC1RAB9ASMN1; SMN2TAAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10672987-B2 Polymer and electronic device and organic thin film transistor including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-06-02 US disclosed
US-20170346013-A1 POLYMER AND ELECTRONIC DEVICE AND ORGANIC THIN FILM TRANSISTOR INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-11-30 US disclosed
US-20170346013-A1 POLYMER AND ELECTRONIC DEVICE AND ORGANIC THIN FILM TRANSISTOR INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-11-30 US disclosed