Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857285 | 0.94 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TSHRNPC1RAB9A | |
| SCHEMBL3856257 | 0.89 | TSHR (0.33) | CYP3A4TSHRKDM4EHSD17B10 | |
| SCHEMBL11696259 | 0.81 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRHPGDTDP1 | |
| SCHEMBL10071546 | 0.77 | NPC1 (0.38) | ALDH1A1CYP3A4NPC1RAB9ATP53 | |
| SCHEMBL10071541 | 0.77 | NPC1 (0.38) | ALDH1A1CYP3A4NPC1RAB9ATP53 | |
| SCHEMBL3848824 | 0.76 | CYP3A4 (0.52) | ALDH1A1CYP3A4TSHRHPGDKMT2A | |
| SCHEMBL3858733 | 0.76 | CYP3A4 (0.52) | ALDH1A1CYP3A4TSHRHPGDKMT2A | |
| SCHEMBL6685337 | 0.76 | CYP3A4 (0.52) | ALDH1A1CYP3A4TSHRHPGDKMT2A | |
| SCHEMBL10071540 | 0.75 | MLNR (0.37) | CYP3A4NPC1RAB9ATP53HPGD | |
| SCHEMBL3899771 | 0.74 | CYP3A4 (0.54) | ALDH1A1CYP3A4TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386470-A1 | COMPOSITION FOR DYEING KERATIN FIBERS | L'OREAL (FR) | 2018-10-17 | — | — | EP | disclosed |
| US-20180256474-A1 | COMPOSITION FOR DYEING KERATIN FIBERS | L'OREAL (FR) | 2018-09-13 | — | — | US | disclosed |
| WO-2017094866-A1 | COMPOSITION FOR DYEING KERATIN FIBERS | L'OREAL (FR) | 2017-06-08 | — | — | WO | disclosed |
| US-7576125-B2 | Melanogenesis inhibitor and skin preparation containing the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-08-18 | — | — | US | disclosed |
| US-20060088485-A1 | Melanogenesis inhibitor and skin preparation containing the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-04-27 | — | — | US | disclosed |
| WO-2004071481-A1 | MELANOGENESIS INHIBITOR AND SKIN PREPARATION CONTAINING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060088485-A1 | Melanogenesis inhibitor and skin preparation containing the same | MC1R, TYR, MITF | ALDH1A1 6/4885CYP3A4 2316/4885TSHR 2223/4885 |
| US-20180256474-A1 | COMPOSITION FOR DYEING KERATIN FIBERS | KRT18, DSG1, DSC1 | ALDH1A1 689/4885CYP3A4 1268/4885TSHR 4741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.