Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849934 | 0.95 | PPARG (0.38) | PPARGPPARAPLA2G4AMGAT2HTT | |
| SCHEMBL3849202 | 0.92 | EPHX2 (0.34) | PKMPLA2G4AEPHX2TSHRMAPK1 | |
| SCHEMBL3841060 | 0.92 | PPARG (0.39) | PPARGPPARAPLA2G4AHTTSMN1; SMN2 | |
| SCHEMBL3841422 | 0.91 | PKM (0.34) | PKMPPARGPPARAPPARDEPHX2 | |
| SCHEMBL3844320 | 0.90 | PPARA (0.40) | PPARGPPARAPPARD | |
| SCHEMBL3851244 | 0.87 | PPARA (0.43) | PPARGPPARAPPARD | |
| SCHEMBL3844532 | 0.87 | PPARA (0.45) | PPARGPPARAPPARD | |
| SCHEMBL3845275 | 0.87 | PPARG (0.42) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL3287514 | 0.85 | PPARA (0.38) | PPARGPPARAPPARDMGAT2P2RX3 | |
| SCHEMBL3843700 | 0.84 | SMPD1 (0.39) | LMNAHTTRAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |