Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947314 | 0.92 | FFAR1 (0.59) | FFAR1S1PR1S1PR3HPGDPTPN1 | |
| SCHEMBL3083583 | 0.88 | FFAR1 (0.60) | FFAR1S1PR1S1PR3HPGDPTPN1 | |
| SCHEMBL3843475 | 0.86 | FFAR1 (0.59) | FFAR1S1PR1S1PR3HPGDPTPN1 | |
| SCHEMBL9098252 | 0.86 | FFAR1 (0.59) | FFAR1S1PR1S1PR3HPGDPTPN1 | |
| SCHEMBL2233399 | 0.86 | HPGD (0.58) | FFAR1S1PR1S1PR3HPGDPTPN1 | |
| SCHEMBL14463874 | 0.86 | LTA4H (0.77) | LTA4HEPHX2FFAR1S1PR1S1PR3 | |
| SCHEMBL1299974 | 0.84 | RAB9A (0.61) | LTA4HFFAR1HPGDPTPN1ALDH1A1 | |
| SCHEMBL465539 | 0.84 | HPGD (0.69) | FFAR1S1PR1S1PR3HPGDPTPN1 | |
| SCHEMBL7293515 | 0.83 | FFAR1 (0.58) | LTA4HFFAR1S1PR1S1PR3LMNA | |
| SCHEMBL945454 | 0.82 | ALDH1A1 (0.61) | HPGDALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009004430-A1 | N-BENZYL OXAZOLIDINONES AND RELATED HETEROCYCLEIC COMPOUNDS AS POTENTIATORS OF GLUTAMATE RECEPTORS | PFIZER INC. (US) | 2009-01-08 | — | — | WO | disclosed |