Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853839 | 0.83 | KCNA3 (0.52) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL10816334 | 0.80 | TLR7 (0.44) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11540422 | 0.80 | ALDH1A1 (0.51) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30808046 | 0.79 | LMNA (0.50) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL28354196 | 0.79 | LMNA (0.50) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL28354200 | 0.76 | LMNA (0.52) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL29695464 | 0.76 | LMNA (0.52) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL15869563 | 0.76 | LMNA (0.63) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL13220789 | 0.75 | KCNA3 (0.58) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL10808933 | 0.75 | BCHE (0.43) | MAPTALDH1A1NPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207891-A1 | Salts of 3-acylamino-benzisothiazole-S,S-dioxides, process for their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1987-01-07 | — | — | EP | claimed |
| WO-2009141065-A2 | (1,2-BENZISOTHIAZOL-3-YL)(THIO)CARBAMATES AND (1,2-BENZISOTHIAZOL-3-YL)(THIO)OXAMATES AND THE OXIDATION FORMS THEREOF FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |
| EP-0110829-B1 | PESTICIDES | CIBA-GEIGY AG (CH) | 1990-12-27 | — | — | EP | disclosed |
| EP-0207891-A1 | Salts of 3-acylamino-benzisothiazole-S,S-dioxides, process for their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1987-01-07 | — | — | EP | disclosed |
| EP-0110829-A2 | Pesticides | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | disclosed |