Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853334 | 0.80 | MAPT (0.51) | ALDH1A1RXFP1VCPEPAS1MAPT | |
| SCHEMBL29853839 | 0.78 | KCNA3 (0.52) | ALDH1A1RXFP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL13220550 | 0.75 | NLRP3 (0.48) | ALDH1A1RXFP1VCPEPAS1MAPT | |
| SCHEMBL13220736 | 0.75 | KCNA3 (0.48) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30896587 | 0.75 | ALDH1A1 (0.50) | ALDH1A1RXFP1EPAS1MAPTLMNA | |
| SCHEMBL30808046 | 0.74 | LMNA (0.50) | ALDH1A1RXFP1EPAS1MAPTLMNA | |
| SCHEMBL28354196 | 0.74 | LMNA (0.50) | ALDH1A1RXFP1EPAS1MAPTLMNA | |
| SCHEMBL13220624 | 0.74 | MAPT (0.61) | ALDH1A1RXFP1MAPTLMNAPOLB | |
| SCHEMBL13220791 | 0.74 | MAPT (0.51) | ALDH1A1RXFP1VCPMAPTLMNA | |
| SCHEMBL13220735 | 0.74 | PPARG (0.46) | ALDH1A1VCPMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148798-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1979-04-10 | — | — | US | disclosed |