Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860377 | 0.93 | DGAT1 (0.53) | DGAT1AAK1USP30PRMT5WDR77 | |
| SCHEMBL283737 | 0.84 | RAB9A (0.51) | BCL2RAB9ANPC1TP53MAPK1 | |
| SCHEMBL29372377 | 0.84 | RAB9A (0.51) | BCL2RAB9ANPC1TP53MAPK1 | |
| SCHEMBL3791054 | 0.81 | DGAT1 (0.54) | DGAT1AAK1USP30 | |
| SCHEMBL30400446 | 0.81 | DGAT1 (0.54) | DGAT1AAK1USP30 | |
| SCHEMBL1180976 | 0.78 | AAK1 (0.47) | DGAT1AAK1USP30PRMT5WDR77 | |
| SCHEMBL19195067 | 0.78 | DGAT1 (0.50) | DGAT1AAK1USP30PRMT5WDR77 | |
| SCHEMBL29967445 | 0.78 | DGAT1 (0.50) | DGAT1AAK1USP30PRMT5WDR77 | |
| SCHEMBL20227776 | 0.78 | GSK3B (0.49) | DGAT1AAK1USP30PRMT5WDR77 | |
| SCHEMBL2119494 | 0.77 | DGAT1 (0.53) | DGAT1AAK1USP30RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861365-B1 | N-SULPHONYLPYRROLES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2009-07-01 | — | — | EP | disclosed |