Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31586013 | 0.85 | KDM4E (0.77) | KDM4ETDP1RORBCYP3A4L3MBTL1 | |
| SCHEMBL912675 | 0.85 | KDM4E (0.77) | KDM4ETDP1RORBCYP3A4L3MBTL1 | |
| SCHEMBL10969548 | 0.85 | RORB (0.60) | KDM4ETDP1RORBCYP3A4L3MBTL1 | |
| SCHEMBL29916420 | 0.81 | KDM4E (0.55) | KDM4ETDP1RORBCYP3A4L3MBTL1 | |
| SCHEMBL13002583 | 0.81 | KDM4E (0.55) | KDM4ETDP1RORBCYP3A4L3MBTL1 | |
| SCHEMBL945856 | 0.81 | KDM4E (0.55) | KDM4ETDP1RORBCYP3A4L3MBTL1 | |
| SCHEMBL11471987 | 0.80 | KMT2A (0.55) | KDM4ETDP1RORBCYP3A4L3MBTL1 | |
| SCHEMBL5670751 | 0.80 | KDM4E (0.48) | KDM4ETDP1CYP3A4L3MBTL1ALDH1A1 | |
| Nitrous Acid SCHEMBL28162396 | 0.79 | KDM4E (0.67) | KDM4ETDP1RORBCYP3A4L3MBTL1 | |
| SCHEMBL3733315 | 0.79 | KDM4E (0.52) | KDM4ETDP1RORBCYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582664-B2 | Acylaminothiazole derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2009-09-01 | — | — | US | disclosed |
| US-20060293365-A1 | ACYLAMINOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293365-A1 | ACYLAMINOTHIAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | ASS1, QTRT2, MLLT1 | KDM4E 225/4885TDP1 2665/4885RORB 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.