SCHEMBL385367

SCHEMBL385367

CCCCc1cccc(OP(=O)(Oc2cccc(CCCC)c2CCCC)Oc2cccc(CCCC)c2CCCC)c1CCCC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.43
PTGS2 P35354 1/20 0.43
PPARA Q07869 2/20 0.41
LTB4R Q15722 1/20 0.40
LTB4R2 Q9NPC1 1/20 0.40
PPARG P37231 1/20 0.40
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
ELANE P08246 1/20 0.36
CTSG P08311 1/20 0.36
TSHR P16473 1/20 0.36
BID P55957 1/20 0.35
BCL2L1 Q07817 1/20 0.35
MCL1 Q07820 1/20 0.35
BAK1 Q16611 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL766607 0.95 PTGS2 (0.49) ALOX5PTGS2PPARALTB4RLTB4R2
SCHEMBL4445994 0.94 PPARA (0.49) ALOX5PTGS2PPARALTB4RLTB4R2
SCHEMBL3861457 0.94 PPARA (0.49) ALOX5PTGS2PPARALTB4RLTB4R2
SCHEMBL4440543 0.94 PPARA (0.49) ALOX5PTGS2PPARALTB4RLTB4R2
SCHEMBL10353669 0.94 PPARA (0.49) ALOX5PTGS2PPARALTB4RLTB4R2
SCHEMBL9332296 0.94 PPARA (0.49) ALOX5PTGS2PPARALTB4RLTB4R2
SCHEMBL207980 0.94 PPARA (0.49) ALOX5PTGS2PPARALTB4RLTB4R2
SCHEMBL4442480 0.94 PPARA (0.49) ALOX5PTGS2PPARALTB4RLTB4R2
SCHEMBL4446488 0.92 LTB4R (0.41) PPARALTB4RLTB4R2
SCHEMBL30476064 0.90 THRA (0.48) ALOX5PTGS2PPARALTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 777 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110997884-B Metal working oil composition and method for producing metal sheet laminate 出光兴产株式会社 2023-06-20 CN claimed
US-11396576-B2 Oriented films and shrink films comprising polyesters which comprise tetramethylcyclobutanediol and ethylene glycol EASTMAN CHEMICAL COMPANY (US) 2022-07-26 US claimed
EP-3312239-A1 POLYCARBONATE COMPOSITION AND PREPARATION METHOD THEREOF Kingfa Sci&Tech Co. Ltd. (CN) 2018-04-25 EP claimed
US-8299204-B2 Polyester compositions which comprise cyclobutanediol and certain thermal stabilizers, and/or reaction products thereof EASTMAN CHEMICAL COMPANY (US) 2012-10-30 US claimed
US-8193302-B2 Polyester compositions which comprise cyclobutanediol and certain phosphate thermal stabilizers, and/or reaction products thereof EASTMAN CHEMICAL COMPANY (US) 2012-06-05 US claimed
EP-1940955-B1 POLYESTER COMPOSITIONS WHICH COMPRISE CYCLOBUTANEDIOL AND CERTAIN THERMAL STABILIZERS, AND/OR REACTION PRODUCTS THEREOF EASTMAN CHEM CO (US) 2010-11-03 EP claimed
US-20100184940-A1 Polyester Compositions Which Comprise Cyclobutanediol and Certain Thermal Stabilizers, and/or Reaction Products Thereof EASTMAN CHEMICAL COMPANY (US) 2010-07-22 US claimed
US-7737246-B2 Polyester compositions which comprise cyclobutanediol, cyclohexanedimethanol, and ethylene glycol and manufacturing processes therefor EASTMAN CHEMICAL COMPANY (US) 2010-06-15 US claimed
EP-2074158-A1 POLYESTER COMPOSITIONS WHICH COMPRISE CYCLOBUTANEDIOL, ETHYLENE GLYCOL, TITANIUM, AND PHOSPHORUS WITH IMPROVED COLOR AND MANUFACTURING PROCESSES THEREFOR Eastman Chemical Company (US) 2009-07-01 EP claimed
EP-2074174-A1 POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANEDIOL, CYCLOHEXANEDIMETHANOL AND ETHYLENE GLYCOL, AND MANUFACTURING PROCESSES THEREFOR Eastman Chemical Company (US) 2009-07-01 EP claimed
US-20070129531-A1 Polyester compositions which comprise cyclobutanediol and certain phosphate thermal stabilizers, and/or reaction products thereof EASTMAN CHEMICAL COMPANY 2007-06-07 US claimed
WO-2007053434-A1 POLYESTER COMPOSITIONS WHICH COMPRISE CYCLOBUTANEDIOL AND CERTAIN THERMAL STABILIZERS, AND/OR REACTION PRODUCTS THEREOF EASTMAN CHEMICAL COMPANY (US) 2007-05-10 WO claimed
EP-1185586-B1 COMPOSITIONS WITH ENHANCED DUCTILITY GEN ELECTRIC (US) 2004-12-15 EP claimed
US-6486244-B2 THERMOPLASTIC FORMULATION; EASE OF HANDLING WITHOUT THE RISK OF DUST IGNITION GENERAL ELECTRIC COMPANY 2002-11-26 US claimed
US-6350804-B2 POLYPHENYLENE ETHER RESIN AND BLENDS CONTAINING POLYPHENYLENE ETHER RESIN, AND AN ORGANOCLAY GENERAL ELECTRIC CO. 2002-02-26 US claimed
EP-1173510-A1 POLYPHENYLENE ETHER RESIN CONCENTRATES CONTAINING ORGANIC PHOSPHATES GENERAL ELECTRIC COMPANY (US) 2002-01-23 EP claimed
US-20010049025-A1 Multilayer films having flame retardant layers 3M INNOVATIVE PROPERTIES COMPANY 2001-12-06 US claimed
US-20010031808-A1 Polyphenylene ether resin concentrates containing organic phosphates GENERAL ELECTRIC CO. 2001-10-18 US claimed
US-6258879-B1 Polyphenylene ether resin concentrates containing organic phosphates GENERAL ELECTRIC COMPANY 2001-07-10 US claimed
WO-2000059995-A1 POLYPHENYLENE ETHER RESIN CONCENTRATES CONTAINING ORGANIC PHOSPHATES GENERAL ELECTRIC COMPANY (US) 2000-10-12 WO claimed