Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | ACHE | P22303 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL11558424 | 1.00 | LMNA (0.65) | LMNAACHETSHRALOX12NOTUM | |
| Benzene SCHEMBL28980473 | 0.94 | LMNA (0.53) | LMNAACHETSHRALOX12NOTUM | |
| Toluene SCHEMBL28219498 | 0.91 | ACHE (0.69) | LMNAACHETSHRALOX12NOTUM | |
| Biphenyl SCHEMBL27604300 | 0.89 | NOTUM (0.70) | LMNAACHETSHRALOX12NOTUM | |
| Toluene SCHEMBL434901 | 0.88 | ACHE (0.65) | LMNAACHETSHRALOX12NOTUM | |
| Pyridine SCHEMBL5590769 | 0.88 | TSHR (0.53) | LMNAACHETSHRALOX12NOTUM | |
| SCHEMBL1310594 | 0.87 | LMNA (0.50) | LMNAACHETSHRALOX12KMT2A | |
| SCHEMBL12062 | 0.87 | — | — | |
| SCHEMBL8486973 | 0.87 | LMNA (0.50) | LMNAACHETSHRALOX12KMT2A | |
| SCHEMBL19443810 | 0.86 | TSHR (0.61) | LMNAACHETSHRALOX12NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073246-A1 | METHOD FOR THE SYNTHESIS OF IRIDIUM (III) COMPLEXES WITH STERICALLY DEMANDING LIGANDS | UNIVERSAL DISPLAY CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009073245-A1 | LIGHT-EMITTING ORGANOMETALLIC COMPLEXES | UNIVERSAL DISPLAY CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |
| US-4151201-A | CONDENSATION OF PHENOLS WITH FORMALDEHYDE WITH A STANNOUS AND/OR STANNIC CHLORIDE CATALYST AND AN APROTIC BINDER | MONTEDISON S.P.A. (IT) | 1979-04-24 | — | — | US | disclosed |
| US-4006149-A | COBALT CONTAINING | STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) | 1977-02-01 | — | — | US | disclosed |