Pyridine

Pyridine

SCHEMBL5590769

Cc1ccncc1.c1ccncc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
NAPRT Q6XQN6 1/20 0.53
LMNA P02545 4/20 0.47
ACHE P22303 2/20 0.47
ALOX12 P18054 1/20 0.47
NOTUM Q6P988 1/20 0.46
MAPT P10636 3/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
CYP2A6 P11509 1/20 0.38
CHRM5 P08912 1/20 0.38
CHKA P35790 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HDAC8 Q9BY41 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28980473 0.94 LMNA (0.53) TSHRTDP1NAPRTLMNAACHE
P-Xylene SCHEMBL1700858 0.91 TDP1 (0.56) TSHRTDP1NAPRTLMNAACHE
P-Xylene SCHEMBL27431590 0.91 TDP1 (0.56) TSHRTDP1NAPRTLMNAACHE
Toluene SCHEMBL434901 0.88 ACHE (0.65) TSHRTDP1NAPRTLMNAACHE
P-Xylene SCHEMBL29229140 0.88 TDP1 (0.53) TSHRTDP1NAPRTLMNAACHE
Toluene SCHEMBL11558424 0.88 LMNA (0.65) TSHRTDP1LMNAACHEALOX12
P-Xylene SCHEMBL10614849 0.88 TDP1 (0.53) TSHRTDP1NAPRTLMNAACHE
P-Xylene SCHEMBL93217 0.88 TDP1 (0.53) TSHRTDP1NAPRTLMNAACHE
Toluene SCHEMBL3854005 0.88 LMNA (0.65) TSHRTDP1LMNAACHEALOX12
Methyl Alcohol SCHEMBL11046402 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591231-A Method for large-scale production of 4-formic acid-2, 2' -bipyridine 河南阿尔法医药科技有限公司 2022-06-07 CN claimed
CN-110416586-B Iron-based flow battery, positive and negative electrolyte thereof and preparation method 江西理工大学 2020-09-11 CN claimed
CN-114591231-B Method for large-scale production of 4-formic acid-2, 2' -bipyridine 河南阿尔法医药科技有限公司 2024-02-20 CN disclosed
US-20230295090-A1 METHOD FOR PREPARING BIPYRIDINE HYUNDAI MOTOR COMPANY (KR) 2023-09-21 US disclosed
CN-111518145-B Cyano-bridged metal organic compound with intramolecular magnetic transformation and preparation method and application thereof 荆楚理工学院 2023-06-20 CN disclosed
CN-114591231-A Method for large-scale production of 4-formic acid-2, 2' -bipyridine 河南阿尔法医药科技有限公司 2022-06-07 CN disclosed
CN-110416586-B Iron-based flow battery, positive and negative electrolyte thereof and preparation method 江西理工大学 2020-09-11 CN disclosed
CN-105712924-A Method for catalyzing and producing pyridine and picoline with modified molecular sieve 广西新天德能源有限公司 2016-06-29 CN disclosed
EP-1774550-A1 2,2 -BIPYRIDINE LIGAND, SENSITIZING DYE AND DYE SENSITIZED SOLAR CELL Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2007-04-18 EP disclosed
WO-2006010290-A1 2, 2-BIPYRIDINE LIGAND, SENSITIZING DYE AND DYE SENSITIZED SOLAR CELL ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2006-02-02 WO disclosed
CN-1223585-C Prepn process of pyridine and methyl pyridine CHINA PETROCHEMICAL CORP (CN) 2005-10-19 CN disclosed
CN-1207284-C Synthesis process of pyridine and methyl pyridine CHINA PETROCHEMICAL CORP (CN) 2005-06-22 CN disclosed
CN-1506354-A Synthesis process of pyridine and methyl pyridine 中国石油化工股份有限公司 2004-06-23 CN disclosed
CN-1506353-A Prepn process of pyridine and methyl pyridine 中国石油化工股份有限公司 2004-06-23 CN disclosed
US-4278745-A IODINE, 2 PYRIDINE-BASED COMPOUNDS MEDTRONIC, INC. (US) 1981-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295090-A1 METHOD FOR PREPARING BIPYRIDINE ITPA, PPIP5K2, PAICS TSHR 2897/4885TDP1 4390/4885NAPRT 1582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.