Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.61 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.61 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.53 |
| ▸ | GAK | O14976 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 3/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624006 | 1.00 | NR4A2 (0.61) | NR4A2SOS2NCF1FERMT2GAK | |
| SCHEMBL16446547 | 0.84 | NR4A2 (0.61) | NR4A2SOS2NCF1FERMT2GAK | |
| SCHEMBL3073397 | 0.79 | NR4A2 (0.66) | NR4A2SOS2NCF1ALDH1A1ACHE | |
| SCHEMBL30044428 | 0.79 | NR4A2 (0.66) | NR4A2SOS2NCF1ALDH1A1ACHE | |
| SCHEMBL6660966 | 0.77 | GRM4 (0.56) | FERMT2GAKGRM4NSD3NSD2 | |
| SCHEMBL596040 | 0.76 | NR4A2 (1.00) | NR4A2SOS2NCF1FERMT2ALDH1A1 | |
| SCHEMBL16705392 | 0.76 | FERMT2 (0.49) | NR4A2SOS2FERMT2GAKGRM4 | |
| SCHEMBL4619603 | 0.76 | FERMT2 (0.49) | FERMT2GAKGRM4CCNCCDK8 | |
| SCHEMBL3319590 | 0.76 | NR4A2 (0.61) | NR4A2SOS2NCF1FERMT2GAK | |
| SCHEMBL3071029 | 0.76 | NR4A2 (0.61) | NR4A2SOS2NCF1ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2090566-A2 | Certain phenylacetic acids and derivatives | Novartis AG (CH) | 2009-08-19 | — | — | EP | disclosed |