SCHEMBL3854530

SCHEMBL3854530

CC#C[C@H](CC(=O)O)c1ccc(OC2CCc3cc(-c4ccccc4OCC)ccc32)cc1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13616868 1.00 FFAR1 (0.69) FFAR1
SCHEMBL13616752 0.92 FFAR1 (0.58) FFAR1
SCHEMBL3853388 0.88 FFAR1 (0.71) FFAR1
SCHEMBL3852671 0.88 FFAR1 (0.71) FFAR1
SCHEMBL13616862 0.88 FFAR1 (0.71) FFAR1
SCHEMBL3859656 0.88 FFAR1 (0.68) FFAR1
SCHEMBL13616864 0.88 FFAR1 (0.68) FFAR1
SCHEMBL3853358 0.87 FFAR1 (0.65) FFAR1
SCHEMBL13616869 0.87 FFAR1 (0.67) FFAR1
SCHEMBL3854753 0.87 FFAR1 (0.67) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5458977-A Electroluminescence device containing a thin film electrode IDEMITSU KOSAN CO., LTD. (JP) 1995-10-17 US claimed
US-5231329-A Organic thin film electroluminescent device NIPPON OIL CO., LTD. (JP) 1993-07-27 US claimed
US-20090275598-A1 Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders AMGEN INC. (US) 2009-11-05 US disclosed
US-20090275598-A1 Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders AMGEN INC. (US) 2009-11-05 US disclosed
US-7585574-B2 Pyrene derivative and organic electroluminescence device making use of the same IDEMITSU KOSAN CO., LTD. (JP) 2009-09-08 US disclosed
US-7582803-B2 Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders AMGEN INC. (US) 2009-09-01 US disclosed
US-7582803-B2 Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders AMGEN INC. (US) 2009-09-01 US disclosed
US-20080124571-A1 PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-29 US disclosed
EP-1924546-A1 CONFORMATIONALLY CONSTRAINED 3- (4-HYDROXY-PHENYL) - SUBSTITUTED-PROPANOIC ACIDS USEFUL FOR TREATING METABOLIC DISORDERS Amgen, Inc (US) 2008-05-28 EP disclosed
EP-1905754-A1 PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-04-02 EP disclosed
WO-2007033002-A1 CONFORMATIONALLY CONSTRAINED 3- (4-HYDROXY-PHENYL) - SUBSTITUTED-PROPANOIC ACIDS USEFUL FOR TREATING METABOLIC DISORDERS AMGEN INC. (US) 2007-03-22 WO disclosed
EP-1162193-B1 Acrylenediamine derivatives and organic electroluminescence device containing the same IDEMITSU KOSAN CO (JP) 2003-05-14 EP disclosed
EP-0721935-B1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ARYLENEDIAMINE DERIVATIVE IDEMITSU KOSAN CO (JP) 2003-01-22 EP disclosed
US-6459199-B1 Multicolor organic EL element having plurality of organic dyes, method of manufacturing the same, and display using the same CHEMIPRO KASEI KAISHA, LIMITED (JP) 2002-10-01 US disclosed
EP-1162193-A1 Acrylenediamine derivatives and organic electroluminescence device containing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 2001-12-12 EP disclosed
US-6284393-B1 USABLE FOR HIGH-RESOLUTION DISPLAY; LUMINOUS EFFICIENCY, LOW RESISTANCE AND TRANSPARENCY; DURABILITY IDEMITSU KOSAN CO., LTD. (JP) 2001-09-04 US disclosed
EP-1119221-A2 Organic electroluminescent device IDEMITSU KOSAN COMPANY LIMITED (JP) 2001-07-25 EP disclosed
EP-1119222-A2 Organic electroluminescent device IDEMITSU KOSAN COMPANY LIMITED (JP) 2001-07-25 EP disclosed
EP-0845924-A2 Organic electroluminescent device IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-06-03 EP disclosed
EP-0721935-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ARYLENEDIAMINE DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-07-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275598-A1 Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders PC, PNLIP, PDHX FFAR1 51/4885
US-20080124571-A1 PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME PPOX, CYBA, EBPL FFAR1 4610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.