Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1221964 | 0.85 | PDCD1 (0.54) | PDCD1CD274APOBEC3GBAZ2BBAZ2A | |
| SCHEMBL28483705 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPK1TAAR1PDCD1CD274 | |
| SCHEMBL110893 | 0.80 | — | — | |
| SCHEMBL10535771 | 0.79 | PDCD1 (0.45) | ALDH1A1PDCD1CD274APOBEC3GBAZ2B | |
| SCHEMBL17051207 | 0.79 | PDCD1 (0.45) | PDCD1CD274APOBEC3GBAZ2BBAZ2A | |
| Lithium Ion SCHEMBL10534528 | 0.78 | PDCD1 (0.48) | PDCD1CD274APOBEC3GBAZ2BBAZ2A | |
| SCHEMBL8067284 | 0.77 | GABRA1 (0.50) | ALDH1A1MAPK1TAAR1IDO1 | |
| SCHEMBL31295703 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPK1TAAR1APOBEC3GIDO1 | |
| SCHEMBL358976 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPK1TAAR1APOBEC3GIDO1 | |
| SCHEMBL1928303 | 0.76 | IDO1 (0.47) | ALDH1A1MAPK1TAAR1APOBEC3GIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016971-B | Antiviral compound | PHARMASSET INC. (US) | 2016-05-25 | — | — | CN | disclosed |
| US-7592487-B2 | Chiral tertiary aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-09-22 | — | — | US | disclosed |
| US-7572927-B2 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20080194816-A1 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1727783-A4 | CHIRAL TERTIARY AMINOALKYLNAPHTHOLS | UNIV HONG KONG POLYTECHNIC (CN) | 2008-03-19 | — | — | EP | disclosed |
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2008-02-21 | — | — | US | disclosed |
| EP-1727783-A1 | CHIRAL TERTIARY AMINOALKYLNAPHTHOLS | The Hong Kong Polytechnic University (CN) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087707-A1 | CHIRAL TERTIARY AMINOALKYLNAPHTHOLS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2005-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194816-A1 | Method of producing an o-disubstituted aromatic compound, and method of producing a monosubstituted-monohaloaromatic compound | DDT, OXER1, OSTC | ALDH1A1 1259/4885MAPK1 2478/4885TAAR1 3009/4885 |
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | ALDH7A1, ADH5, ALDH1A1 | ALDH1A1 3/4885MAPK1 3690/4885TAAR1 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.