Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | CASP6 | P55212 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | CTSV | O60911 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30982031 | 1.00 | ALDH1A1 (0.67) | ALDH1A1GAALMNAKDM4EGLA | |
| SCHEMBL14543828 | 0.90 | HSD17B10 (0.59) | ALDH1A1GAALMNAKDM4EGLA | |
| SCHEMBL30933343 | 0.90 | HSD17B10 (0.59) | ALDH1A1GAALMNAKDM4EGLA | |
| SCHEMBL9709050 | 0.89 | GAA (0.67) | ALDH1A1GAALMNAKDM4EGLA | |
| SCHEMBL10171024 | 0.87 | HSD17B10 (0.53) | ALDH1A1GAALMNAKDM4EGLA | |
| SCHEMBL4653063 | 0.86 | HSD17B10 (0.56) | ALDH1A1GAALMNAKDM4EGLA | |
| SCHEMBL11468715 | 0.86 | ALDH1A1 (0.53) | ALDH1A1GAALMNAKDM4EGLA | |
| SCHEMBL262450 | 0.84 | AHR (0.64) | ALDH1A1KDM4EHPGDATMMEN1 | |
| SCHEMBL30388549 | 0.84 | AHR (0.64) | ALDH1A1KDM4EHPGDATMMEN1 | |
| SCHEMBL18381874 | 0.82 | AHR (0.61) | ALDH1A1LMNAKDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123663-A1 | ANTIMICROBIAL COMPOUNDS | SRI INTERNATIONAL (US) | 2024-06-13 | — | — | WO | disclosed |
| CN-106699659-B | A kind of N- phenylacridine ketone electroluminescent organic material and its preparation method and application | 中节能万润股份有限公司 | 2018-12-18 | — | — | CN | disclosed |
| US-9899604-B2 | Compound for organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2018-02-20 | — | — | US | disclosed |
| US-9899604-B2 | Compound for organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2018-02-20 | — | — | US | disclosed |
| US-20140225083-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE | CHEIL INDUSTRIES INC. (KR) | 2014-08-14 | — | — | US | disclosed |
| US-20140225083-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE | CHEIL INDUSTRIES INC. (KR) | 2014-08-14 | — | — | US | disclosed |
| US-20140225083-A1 | COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE | CHEIL INDUSTRIES INC. (KR) | 2014-08-14 | — | — | US | disclosed |
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| EP-1687275-A4 | PYRIDIN-4-YLAMINE COMPOUNDS USEFUL IN THE TREATMENT OF NEUROPATHIC PAIN | MERCK & CO INC (US) | 2009-01-14 | — | — | EP | disclosed |
| US-20070099950-A1 | Pyridin-4-ylamine compounds useful in the treatment of neuropathic pain | AGT SCIENCE LIMITED (GB) | 2007-05-03 | — | — | US | disclosed |
| EP-0591583-B1 | Benzo (f) quinolinones as 5-alpha-reductase inhibitors | LILLY CO ELI (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-0532190-B1 | Benzo(f)quinolinones as 5-alpha-reductase inhibitors | LILLY CO ELI (US) | 2000-12-27 | — | — | EP | disclosed |
| US-5710163-A | STEROID 5A-REDUCTASE INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5670512-A | SKIN DISORDERS; REDUCTASE INHIBITORS | ELI LILLY AND COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| US-5541190-A | TREATING BENIGN PROSTATIC HYPERPLASIA, MALE PATTERN BALDNESS, PROSTATIC CANCER, ANDROGENIC ALOPECIA | ELI LILLY AND COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| US-5495021-A | STEROID 5 ALPHA-REDUCTASE INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-27 | — | — | US | disclosed |
| US-5334767-A | Steroid 5a-reductase inhibitor | ELI LILLY AND COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0591583-A1 | Benzo (f) quinolinones as 5-alpha-reductase inhibitors | ELI LILLY AND COMPANY (US) | 1994-04-13 | — | — | EP | disclosed |
| US-5239075-A | PROCESS FOR THE PREPARATION OF BENZO (F) QUINOLINONES | ELI LILLY AND COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0532190-A2 | Benzo f quinolinones as 5-alpha-reductase inhibitors | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099950-A1 | Pyridin-4-ylamine compounds useful in the treatment of neuropathic pain | PER2, CNR2, OPRD1 | ALDH1A1 2085/4885GAA 2422/4885LMNA 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.