Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820206 | 0.80 | KMT2A (0.54) | KCNK3KCNK9KMT2AMAPTTSHR | |
| SCHEMBL22979105 | 0.78 | IMPDH2 (0.48) | KMT2AMAPTTSHRMEN1MAPK1 | |
| SCHEMBL1620743 | 0.75 | RAB9A (0.60) | KCNK3KCNK9KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7028467 | 0.75 | KCNK3 (0.59) | KCNK3KCNK9KMT2AMAPTMEN1 | |
| SCHEMBL30542576 | 0.74 | KMT2A (0.48) | KMT2AMAPTTSHRMEN1SMN1; SMN2 | |
| SCHEMBL7160516 | 0.73 | KCNK3 (0.65) | KCNK3KCNK9KMT2AMAPTTSHR | |
| SCHEMBL22987946 | 0.73 | TSHR (0.53) | KMT2AMAPTTSHRMAPK1SMN1; SMN2 | |
| SCHEMBL25375720 | 0.73 | ALDH1A1 (0.52) | KMT2AMAPTTSHRMEN1MAPK1 | |
| Water SCHEMBL27147733 | 0.71 | IRAK4 (0.61) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7018503 | 0.71 | MAPK1 (0.51) | KCNK3KCNK9KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2062050-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | Senomyx, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008154221-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-18 | — | — | WO | disclosed |