Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16439911 | 0.82 | MAOB (0.46) | ALDH1A1TSHRMAOBNFE2L2CYP2C19 | |
| SCHEMBL16439910 | 0.82 | MAOB (0.46) | ALDH1A1TSHRMAOBNFE2L2CYP2C19 | |
| SCHEMBL10415153 | 0.78 | MAOB (0.42) | ALDH1A1TSHRMAOBNFE2L2CYP2C19 | |
| SCHEMBL10415151 | 0.78 | MAOB (0.42) | ALDH1A1TSHRMAOBNFE2L2CYP2C19 | |
| SCHEMBL5352063 | 0.77 | MAOB (0.41) | ALDH1A1TSHRMAOBNFE2L2CYP2C19 | |
| SCHEMBL10522046 | 0.77 | MAOB (0.41) | ALDH1A1TSHRMAOBNFE2L2CYP2C19 | |
| SCHEMBL7174980 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRMAOBNFE2L2CYP2C19 | |
| SCHEMBL115403 | 0.77 | NFE2L2 (0.54) | ALDH1A1TSHRMAOBNFE2L2CYP2C19 | |
| SCHEMBL9800772 | 0.77 | NFE2L2 (0.54) | ALDH1A1TSHRMAOBNFE2L2CYP2C19 | |
| SCHEMBL2875295 | 0.77 | NFE2L2 (0.54) | ALDH1A1TSHRMAOBNFE2L2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202269-A1 | DENSE MODIFIED SILICA WITH SILANE COMPOUNDS AND METHODS OF MAKING AND USING SAME | SABIC GLOBAL TECHNOLOGIES, B.V. (NL) | 2021-10-07 | — | — | WO | claimed |
| WO-2021202269-A1 | DENSE MODIFIED SILICA WITH SILANE COMPOUNDS AND METHODS OF MAKING AND USING SAME | SABIC GLOBAL TECHNOLOGIES, B.V. (NL) | 2021-10-07 | — | — | WO | disclosed |
| EP-2111241-A2 | STENT WITH DIFFERENTIAL TIMING OF ABLUMINAL AND LUMINAL RELEASE OF A THERAPEUTIC AGENT | Boston Scientific Limited (BB) | 2009-10-28 | — | — | EP | disclosed |
| WO-2008063539-A2 | STENT WITH DIFFERENTIAL TIMING OF ABLUMINAL AND LUMINAL RELEASE OF A THERAPEUTIC AGENT | BOSTON SCIENTIFIC LIMITED (BB) | 2008-05-29 | — | — | WO | disclosed |