Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29183057 | 0.85 | SMPD1 (0.48) | L3MBTL1NPC1RAB9ASMPD1HDAC1 | |
| SCHEMBL28542752 | 0.84 | ALDH1A1 (0.56) | MEN1KMT2ABCHEKDM4EL3MBTL1 | |
| SCHEMBL7123571 | 0.83 | KDM4E (0.52) | MEN1KMT2AKDM4EL3MBTL1POLB | |
| SCHEMBL8043023 | 0.82 | KDM4E (0.52) | PDE4DMEN1KMT2ABCHEKDM4E | |
| SCHEMBL3456646 | 0.80 | HPGD (0.52) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL8032637 | 0.79 | POLB (0.51) | PDE4DBCHEKDM4EL3MBTL1POLB | |
| SCHEMBL3848203 | 0.78 | BCHE (0.51) | BCHEKDM4EL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL2988197 | 0.77 | L3MBTL1 (0.56) | MEN1KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL31757763 | 0.77 | L3MBTL1 (0.56) | MEN1KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL25291928 | 0.77 | SMN1; SMN2 (0.51) | BCHENPC1RAB9ASMPD1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740225-A4 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL MYERS SQUIBB CO (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1740225-A2 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | Bristol-Myers Squibb Company (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105159-A2 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-11-10 | — | — | WO | disclosed |