Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988197 | 1.00 | L3MBTL1 (0.56) | L3MBTL1HTR1ADRD2GAABRD4 | |
| SCHEMBL8783688 | 0.88 | L3MBTL1 (0.51) | L3MBTL1HTR1ADRD2GAABRD4 | |
| SCHEMBL28085585 | 0.86 | FFAR4 (0.49) | L3MBTL1BRD4LMNAMAPTPTGER1 | |
| SCHEMBL8324677 | 0.86 | L3MBTL1 (0.64) | L3MBTL1HTR1ADRD2GAABRD4 | |
| SCHEMBL16396466 | 0.85 | MAOB (0.55) | HTR1ADRD2GAAABCB1LMNA | |
| SCHEMBL14678467 | 0.85 | HTR1A (0.60) | HTR1ADRD2LMNAMEN1ALDH1A1 | |
| SCHEMBL5661211 | 0.85 | TBXAS1 (0.53) | L3MBTL1HTR1ADRD2GAABRD4 | |
| SCHEMBL3930253 | 0.85 | HTR1A (0.59) | L3MBTL1HTR1ADRD2GAABRD4 | |
| SCHEMBL5446276 | 0.84 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL68571 | 0.84 | L3MBTL1 (0.69) | L3MBTL1HTR1ADRD2GAABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008758-A1 | LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED | 2026-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008758-A1 | LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | DPP3, DPP7, DPP9 | L3MBTL1 674/4885HTR1A 864/4885DRD2 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.