SCHEMBL3857012

SCHEMBL3857012

c1ccc2c(c1)ccc1n[nH]nc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP2A6 P11509 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP3A4 P08684 1/20 0.45
TDO2 P48775 2/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
HPRT1 P00492 1/20 0.42
PRMT5 O14744 1/20 0.42
PRMT3 O60678 1/20 0.42
CARM1 Q86X55 1/20 0.42
EHMT2 Q96KQ7 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
PRMT1 Q99873 1/20 0.42
WDR77 Q9BQA1 1/20 0.42
SLC2A1 P11166 1/20 0.42
MAOA P21397 1/20 0.42
KEAP1 Q14145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5470832 0.77 PRMT5 (0.56) TSHRALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL15797613 0.75 SMN1; SMN2 (0.43) TSHRALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL5473804 0.75 PRMT5 (0.59) TSHRALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL5466728 0.72 HPRT1 (0.57) TSHRALDH1A1HSD17B10CYP2A6TDP1
Benzo[A]Phenazine SCHEMBL29618896 0.71 ALDH1A1 (0.55) TSHRALDH1A1HSD17B10CYP2A6TDP1
Benzo[A]Phenazine SCHEMBL88133 0.71 ALDH1A1 (0.55) TSHRALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL17897154 0.71 TSHR (0.50) TSHRTDO2KEAP1NFE2L2SMN1; SMN2
SCHEMBL21011556 0.71 TSHR (0.48) TSHRALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL5201632 0.70 ALDH1A1 (0.46) TSHRALDH1A1HSD17B10CYP2A6TDP1
SCHEMBL13156543 0.70 PRMT5 (0.54) TSHRALDH1A1HSD17B10CYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1255797-B2 METHOD FOR ROUGHENING COPPER SURFACES FOR BONDING TO SUBSTRATES OMG ELECTRONIC CHEMICALS INC (US) 2016-10-12 EP claimed
EP-1255797-B1 METHOD FOR ROUGHENING COPPER SURFACES FOR BONDING TO SUBSTRATES OMG ELECTRONIC CHEMICALS INC (US) 2012-06-13 EP claimed
EP-1639047-B1 HETEROCYCLIC COLORANTS BASED ON DIAZABENZOISOINDOLES CLARIANT PRODUKTE DEUTSCHLAND (DE) 2008-04-23 EP claimed
US-20070264600-A1 Heterocyclic Colorants Based on Diazabenzoisoindoles CLARIANT GMBH (DE) 2007-11-15 US claimed
CN-1451031-A Method for roughening copper surfaces for bonding to substrates ELECTROCHEMICALS INC (US) 2003-10-22 CN claimed
EP-4715023-A1 HEAT TRANSFER FLUID ExxonMobil Technology and Engineering Company (US) 2026-03-25 EP disclosed
EP-4715960-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT Dr. Ing. h.c. F. Porsche Aktiengesellschaft (DE) 2026-03-25 EP disclosed
WO-2025108836-A1 COMPOSITIONS FOR REMOVING PHOTORESIST AND ETCH RESIDUES, METHODS OF USING AND USE THEREOF MERCK PATENT GMBH (DE) 2025-05-30 WO disclosed
EP-4453152-A1 ENGINE OIL LUBRICANT COMPOSTIONS AND METHODS FOR MAKING SAME WITH SUPERIOR OIL CONSUMPTION ExxonMobil Technology and Engineering Company (US) 2024-10-30 EP disclosed
CN-117940542-A Process for preparing spray-dried detergent granules 联合利华知识产权控股有限公司 2024-04-26 CN disclosed
EP-3763789-B1 MICROCAPSULE-TYPE TEMPERATURE CHANGE PIGMENT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND TEMPERATURE CHANGE INK AND USE THEREOF WUHAN ZHONGKE ADVANCED MATERIAL TECH CO LTD (CN) 2023-11-08 EP disclosed
WO-2023122405-A1 ENGINE OIL LUBRICANT COMPOSTIONS AND METHODS FOR MAKING SAME WITH SUPERIOR OIL CONSUMPTION ExxonMobil Technology and Engineering Company (US) 2023-06-29 WO disclosed
EP-1255797-A1 METHOD FOR ROUGHENING COPPER SURFACES FOR BONDING TO SUBSTRATES ELECTROCHEMICALS INC. (US) 2002-11-13 EP disclosed
EP-1222158-A1 RADICAL SCAVENGER THE PROCTER & GAMBLE COMPANY (US) 2002-07-17 EP disclosed
US-20020084441-A1 Method for roughening copper surfaces for bonding to substrates MACDERMID, INCORPORATED 2002-07-04 US disclosed
WO-2001049805-A1 METHOD FOR ROUGHENING COPPER SURFACES FOR BONDING TO SUBSTRATES ELECTROCHEMICALS INC. (US) 2001-07-12 WO disclosed
WO-2001028973-A1 RADICAL SCAVENGER THE PROCTER & GAMBLE COMPANY (US) 2001-04-26 WO disclosed
EP-0551413-A1 DETERGENT COMPOSITIONS CONTAINING POLYHYDROXY FATTY ACID AMIDE AND ALKYL BENZENE SULFONATE. PROCTER & GAMBLE (US) 1993-07-21 EP disclosed
CN-1072950-A Detergent formulation PROCTER & GAMBLE (US) 1993-06-09 CN disclosed
WO-1992006150-A1 DETERGENT COMPOSITIONS CONTAINING POLYHYDROXY FATTY ACID AMIDE AND ALKYL BENZENE SULFONATE THE PROCTER & GAMBLE COMPANY (US) 1992-04-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070264600-A1 Heterocyclic Colorants Based on Diazabenzoisoindoles DDT, CDK4, CDK13 TSHR 2532/4885ALDH1A1 120/4885HSD17B10 294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.