SCHEMBL3857163

SCHEMBL3857163

Cc1cc(-n2nnc3cc(Cl)ccc32)c(O)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ TYR P14679 1/20 0.41
▸ KCNMA1 Q12791 4/20 0.40
▸ CHEK1 O14757 1/20 0.37
▸ LIMK1 P53667 1/20 0.37
▸ MAPK14 Q16539 1/20 0.37
▸ CLK4 Q9HAZ1 1/20 0.37
▸ HSPA5 P11021 1/20 0.35
▸ CYP2C9 P11712 2/20 0.35
▸ CYP2C19 P33261 2/20 0.35
▸ HIF1A Q16665 2/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ NPC1 O15118 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ NR1I2 O75469 1/20 0.33
▸ RXRA P19793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5031381 0.90 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL2356484 0.88 KCNMA1 (0.40) POLBKCNMA1CHEK1LIMK1MAPK14
SCHEMBL3177701 0.81 KCNMA1 (0.40) SMN1; SMN2KCNMA1CHEK1LIMK1MAPK14
Bumetrizole SCHEMBL1792777 0.79 KCNMA1 (0.48) SMN1; SMN2ALDH1A1POLBKCNMA1CYP2C9
SCHEMBL22326123 0.77 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1CA2POLBTYR
Bumetrizole SCHEMBL2398487 0.76 NPC1 (0.53) SMN1; SMN2ALDH1A1CA2POLBTYR
Bumetrizole SCHEMBL8054070 0.76 NPC1 (0.53) SMN1; SMN2ALDH1A1CA2POLBTYR
Bumetrizole SCHEMBL8056551 0.76 NPC1 (0.53) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL3179989 0.76 KCNMA1 (0.51) SMN1; SMN2ALDH1A1POLBKCNMA1NPC1
Bumetrizole SCHEMBL8603228 0.76 NPC1 (0.53) SMN1; SMN2ALDH1A1CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327464-A Silane modified polyether sealant and preparation method and application thereof 广州集泰化工股份有限公司 2024-01-02 — — CN claimed
CN-113912752-B Composite polymerization inhibitor and application thereof, high-stability polyether for polycarboxylate superplasticizer and preparation method of high-stability polyether 科之杰新材料集团有限公司 2023-08-29 — — CN claimed
CN-116144308-A Flame-retardant silane modified polyether sealant and preparation method and application thereof 广州集泰化工股份有限公司 2023-05-23 — — CN claimed
CN-112571880-A Electronic paper transparent plastic front panel and preparation method thereof 苏州赛伍应用技术股份有限公司 2021-03-30 — — CN claimed
CN-118292138-A Biodegradable fiber, biodegradable nonwoven fabric, preparation method and application 杭州合材科技有限公司 2024-07-05 — — CN disclosed
CN-114932729-B Decorative sheet and decorative material using same 大日本印刷株式会社 2024-06-21 — — CN disclosed
CN-114423742-B Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-05-28 — — CN disclosed
CN-118006112-A Biodegradable liquid mulching film and preparation method and application thereof 杭州合材科技有限公司 2024-05-10 — — CN disclosed
CN-113227856-B Optical film, polarizing element protective film, transfer body for polarizing element protective film, polarizing plate, image display device, and method for producing polarizing element protective film 大日本印刷株式会社 2024-01-30 — — CN disclosed
CN-117466830-A Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-01-30 — — CN disclosed
CN-117388969-A Optical film, polarizing plate, and image display device 大日本印刷株式会社 2024-01-12 — — CN disclosed
CN-117327464-A Silane modified polyether sealant and preparation method and application thereof 广州集泰化工股份有限公司 2024-01-02 — — CN disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 — — US disclosed
US-20060210908-A1 Image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2006-09-21 — — US disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 — — US disclosed
US-6576388-B2 Multilayer electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the photoreceptor RICOH COMPANY LIMITED (JP) 2003-06-10 — — US disclosed
US-20020197549-A1 Multilayer electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the photoreceptor RICOH COMPANY LIMITED (JP) 2002-12-26 — — US disclosed
EP-0107805-A2 Mixed 2,2,6,6-tetramethyl piperidinyl carboxylic acid ester and amide light stabilizers and stabilized synthetic polymers ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1984-05-09 — — EP disclosed
US-4368258-A HYDROPHOBIC SUBSTANCE, WATER-MISCIBLE SOLVENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1983-01-11 — — US disclosed
US-4232118-A METHINECYANINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-11-04 — — US disclosed
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