SCHEMBL3857541

SCHEMBL3857541

COC(=O)C(=C(C(=O)OC)c1c(C)sc2ccccc12)c1c(C)sc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
MAPK1 P28482 2/20 0.54
L3MBTL1 Q9Y468 4/20 0.46
ATM Q13315 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 4/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.45
GAA P10253 2/20 0.45
MAPT P10636 2/20 0.45
MEN1 O00255 1/20 0.45
GLA P06280 1/20 0.45
ALOX15 P16050 1/20 0.45
HSD17B10 Q99714 1/20 0.45
NPC1 O15118 2/20 0.44
CNR2 P34972 6/20 0.43
CNR1 P21554 3/20 0.43
LIMK1 P53667 1/20 0.39
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3857539 1.00 LMNA (0.54) LMNAMAPK1L3MBTL1ATMTDP1
SCHEMBL3599532 0.83 LMNA (0.71) LMNAMAPK1L3MBTL1ATMTDP1
SCHEMBL9756955 0.81 LMNA (0.46) LMNAMAPK1L3MBTL1ATMTDP1
SCHEMBL9756952 0.81 LMNA (0.46) LMNAMAPK1L3MBTL1ATMTDP1
SCHEMBL9212799 0.81 LMNA (0.48) LMNAMAPK1L3MBTL1ATMTDP1
SCHEMBL27559507 0.80 LMNA (0.47) LMNAMAPK1L3MBTL1ATMTDP1
SCHEMBL1398747 0.78 PRNP (0.53) LMNAMAPK1L3MBTL1ATMTDP1
SCHEMBL29448323 0.78 PRNP (0.53) LMNAMAPK1L3MBTL1ATMTDP1
SCHEMBL9556945 0.78 LMNA (0.49) LMNAMAPK1L3MBTL1ATMTDP1
SCHEMBL31350344 0.76 LIMK1 (0.56) LMNAMAPK1ATMALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 US disclosed
EP-1637570-B1 Color-memorizing photochromic writing instrument PILOT INK CO LTD (JP) 2007-06-27 EP disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 US disclosed
EP-1637570-A1 Color-memorizing photochromic writing instrument THE PILOT INK CO., LTD. (JP) 2006-03-22 EP disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 EP disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 EP disclosed