Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756952 | 1.00 | LMNA (0.46) | LMNAMAPK1ALDH1A1TDP1KDM4E | |
| SCHEMBL13766669 | 0.86 | LMNA (0.39) | LMNAMAPK1ALDH1A1TDP1KDM4E | |
| SCHEMBL1398747 | 0.85 | PRNP (0.53) | LMNAMAPK1ALDH1A1TDP1KDM4E | |
| SCHEMBL29448323 | 0.85 | PRNP (0.53) | LMNAMAPK1ALDH1A1TDP1KDM4E | |
| SCHEMBL13766683 | 0.82 | LMNA (0.36) | LMNAMAPK1ALDH1A1TDP1KDM4E | |
| SCHEMBL9556945 | 0.81 | LMNA (0.49) | LMNAMAPK1ALDH1A1TDP1KDM4E | |
| SCHEMBL3857541 | 0.81 | LMNA (0.54) | LMNAMAPK1ALDH1A1TDP1KDM4E | |
| SCHEMBL3857539 | 0.81 | LMNA (0.54) | LMNAMAPK1ALDH1A1TDP1KDM4E | |
| SCHEMBL31350344 | 0.80 | LIMK1 (0.56) | LMNAMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL6840465 | 0.79 | LMNA (0.41) | LMNAMAPK1ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3014538-A | — | — | None | — | — | JP | disclosed |
| JP-H0314538-A | PRODUCTION OF DIARYLMALEIC ACID DERIVATIVE AND DIARYLETHENE | KANEBO LTD | 1991-01-23 | — | — | JP | disclosed |