Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.30 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.30 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458848 | 0.89 | APP (0.37) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL5157922 | 0.85 | PRSS1 (0.40) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL5428576 | 0.84 | PRSS1 (0.41) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6228804 | 0.77 | ALDH1A1 (0.55) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL855273 | 0.76 | KCNH2 (0.38) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6228247 | 0.76 | ALDH1A1 (0.53) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL1719575 | 0.76 | ALDH1A1 (0.53) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL145850 | 0.75 | ALDH1A1 (0.47) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL33766 | 0.75 | APP (0.48) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL34107 | 0.75 | PRSS1 (0.54) | PRSS1F2PRSS2PRSS3TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | KRT18, CDC73, DSP | PRSS1 2054/4885F2 2385/4885PRSS2 1348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.