Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.32 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.32 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.30 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.30 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857749 | 0.89 | PRSS1 (0.38) | APPFCGR3BFCGR1AFCGR2ACNR1 | |
| SCHEMBL33766 | 0.78 | APP (0.48) | APPFCGR3BFCGR1AFCGR2AMAPT | |
| SCHEMBL14594036 | 0.77 | APP (0.39) | APPMAPTRAB9AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL8420321 | 0.77 | APP (0.47) | APPFCGR3BFCGR1AFCGR2AMAPT | |
| Hydrochloric Acid SCHEMBL21056194 | 0.77 | APP (0.47) | APPFCGR3BFCGR1AFCGR2AMAPT | |
| Ethane SCHEMBL27531493 | 0.75 | APP (0.46) | APPFCGR3BFCGR1AFCGR2AMAPT | |
| SCHEMBL29221782 | 0.73 | MAPT (0.50) | APPFCGR3BFCGR1AFCGR2AMAPT | |
| SCHEMBL5155265 | 0.73 | APP (0.44) | APPMAPTRAB9AMAOAMAOB | |
| SCHEMBL5393286 | 0.73 | APP (0.44) | APPMAPTRAB9AMAOAMAOB | |
| SCHEMBL20473718 | 0.73 | ADRB2 (0.37) | APPFCGR3BFCGR1AFCGR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013069166-A1 | COSMETIC COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| CN-102971290-A | Cationic 6-aminoindolines, dyeing compositions containing them, processes and uses thereof | OREAL | 2013-03-13 | — | — | CN | disclosed |
| EP-2464424-A1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | L'Oréal (FR) | 2012-06-20 | — | — | EP | disclosed |
| WO-2012032673-A1 | COSMETIC COMPOSITION FOR KERATIN FIBERS | L'OREAL (FR) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011138838-A1 | READY-TO-USE COSMETIC COMPOSITION FOR OXIDATION DYEING KERATIN FIBERS | L'OREAL (FR) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011018483-A1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | L'OREAL (FR) | 2011-02-17 | — | — | WO | disclosed |
| WO-2010142776-A1 | N-OXIDIZED AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM SECONDARY, N-ALKYLAMINATED PARA-PHENYLENEDIAMINES, METHOD OF HAIR DYEING USING THESE DYES | L'OREAL (FR) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142777-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM SECONDARY, N-ALKYLAMINATED PARA-PHENYLENEDIAMINES, METHOD OF HAIR DYEING USING THESE DYES | L'OREAL (FR) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142777-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM SECONDARY, N-ALKYLAMINATED PARA-PHENYLENEDIAMINES, METHOD OF HAIR DYEING USING THESE DYES | L'OREAL (FR) | 2010-12-16 | — | — | WO | disclosed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | KRT18, CDC73, DSP | APP 676/4885FCGR3B 4607/4885FCGR1A 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.