Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.35 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880890 | 0.99 | THRB (0.50) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| Iodide SCHEMBL3861985 | 0.97 | THRB (0.49) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL718579 | 0.97 | THRB (0.49) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL3861968 | 0.90 | THRB (0.43) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL9794903 | 0.84 | THRB (0.53) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| Bromide SCHEMBL3858373 | 0.81 | HTT (0.40) | THRBALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL4401452 | 0.79 | HTT (0.41) | THRBALDH1A1KDM4ESMN1; SMN2TSHR | |
| Iodide SCHEMBL3858235 | 0.78 | HTT (0.40) | THRBALDH1A1KDM4ESMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL166561 | 0.78 | HTT (0.40) | THRBALDH1A1KDM4ESMN1; SMN2TSHR | |
| Bromide SCHEMBL11522557 | 0.77 | TSHR (0.48) | THRBALDH1A1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937733-B1 | PROCESS FOR PREPARING AN AQUEOUS DISPERSION OF A QUATERNARY AMMONIUM SALT CONTAINING VINYL COPOLYMER | BOSTIK INC (US) | 2009-12-30 | — | — | EP | claimed |
| US-7619033-B2 | Continuous solution polymerization of vinyl-functional cationic monomers, hydrophobic vinyl monomers, and free radical initiator | BOSTIK, INC. (US) | 2009-11-17 | — | — | US | claimed |
| US-7592391-B2 | Solution polymerizing vinyl-functional cationic monomers, hydrophobic vinyl monomers, vinyl monomers with linear or branched alkyl groups longer than 4 carbons, alkyl hydroxy, polyoxyalkylene, or other functional group, and a free radical initiator | BOSTIK, INC. (US) | 2009-09-22 | — | — | US | claimed |
| EP-1756182-B1 | PROCESS FOR PREPARING AN AQUEOUS DISPERSION OF A QUATERNARY AMMONIUM SALT CONTAINING VINYL COPOLYMER | BOSTIK INC (US) | 2009-02-18 | — | — | EP | claimed |
| EP-1937733-A1 | PROCESS FOR PREPARING AN AQUEOUS DISPERSION OF A QUATERNARY AMMONIUM SALT CONTAINING VINYL COPOLYMER | Bostik, Inc. (US) | 2008-07-02 | — | — | EP | claimed |
| JP-2007529601-A | — | — | 2007-10-25 | — | — | JP | claimed |
| EP-1539259-B1 | WET WIPES COMPRISING ION TRIGGERABLE, CATIONIC POLYMERS | KIMBERLY CLARK CO (US) | 2007-07-25 | — | — | EP | claimed |
| WO-2007035495-A1 | PROCESS FOR PREPARING AN AQUEOUS DISPERSION OF A QUATERNARY AMMONIUM SALT CONTAINING VINYL COPOLYMER | BOSTIK, INC. (US) | 2007-03-29 | — | — | WO | claimed |
| EP-1756182-A1 | PROCESS FOR PREPARING AN AQUEOUS DISPERSION OF A QUATERNARY AMMONIUM SALT CONTAINING VINYL COPOLYMER | Bostik, Inc. (US) | 2007-02-28 | — | — | EP | claimed |
| US-7157389-B2 | Ion triggerable, cationic polymers, a method of making same and items using same | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2007-01-02 | — | — | US | claimed |
| WO-2005090422-A1 | PROCESS FOR PREPARING AN AQUEOUS DISPERSION OF A QUATERNARY AMMONIUM SALT CONTAINING VINYL COPOLYMER | BOSTIK, INC. (US) | 2005-09-29 | — | — | WO | claimed |
| EP-1539259-A1 | ION TRIGGERABLE, CATIONIC POLYMERS, A METHOD OF MAKING SAME AND ITEMS USING SAME | Kimberly-Clark Worldwide, Inc. (US) | 2005-06-15 | — | — | EP | claimed |
| EP-1539880-A1 | IMPROVED ION TRIGGERABLE, CATIONIC POLYMERS, A METHOD OF MAKING SAME AND ITEMS USING SAME | Kimberly-Clark Worldwide, Inc. (US) | 2005-06-15 | — | — | EP | claimed |
| US-20040062791-A1 | Ion triggerable, cationic polymers, a method of making same and items using same | KIMBERLY-CLARK WORLDWIDE, INC. | 2004-04-01 | — | — | US | claimed |
| WO-2004026354-A1 | ION TRIGGERABLE, CATIONIC POLYMERS, A METHOD OF MAKING SAME AND ITEMS USING SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026351-A2 | IMPROVED ION TRIGGERABLE, CATIONIC POLYMERS, A METHOD OF MAKING SAME AND ITEMS USING SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026958-A1 | IMPROVED ION TRIGGERABLE, CATIONIC POLYMERS, A METHOD OF MAKING SAME AND ITEMS USING SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026352-A1 | USE AS BINDER OF ION TRIGGERABLE, VINYL-BASED CATIONIC POLYMERS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2004-04-01 | — | — | WO | claimed |
| US-20040058606-A1 | Ion triggerable, cationic polymers, a method of making same and items using same | KIMBERLY-CLARK WORLDWIDE, INC. | 2004-03-25 | — | — | US | claimed |
| US-20040055704-A1 | Ion triggerable, cationic polymers, a method of making same and items using same | KIMBERLY-CLARK WORLDWIDE, INC. | 2004-03-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040062791-A1 | Ion triggerable, cationic polymers, a method of making same and items using same | PWWP2B, DSG1, WDR1 | HTR1A 4543/4885SLC6A3 2999/4885CHRM2 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.