Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.39 |
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.36 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.35 |
| ▸ | SCN1A known ✓ | P35498 | 1/20 | 0.35 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.35 |
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A known ✓ | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A known ✓ | Q9NY46 | 1/20 | 0.35 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880890 | 0.99 | THRB (0.50) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| Bromide SCHEMBL3857939 | 0.97 | THRB (0.49) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| Iodide SCHEMBL3861985 | 0.97 | THRB (0.49) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL3861968 | 0.90 | THRB (0.43) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL9794903 | 0.87 | THRB (0.53) | THRBALDH1A1KDM4ESMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL166561 | 0.81 | HTT (0.40) | THRBALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL4401452 | 0.79 | HTT (0.41) | THRBALDH1A1KDM4ESMN1; SMN2TSHR | |
| Iodide SCHEMBL3858235 | 0.78 | HTT (0.40) | THRBALDH1A1KDM4ESMN1; SMN2TSHR | |
| Bromide SCHEMBL3858373 | 0.78 | HTT (0.40) | THRBALDH1A1KDM4ESMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL17644160 | 0.77 | TSHR (0.48) | THRBALDH1A1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119980753-A | Papermaking method for improving paper strength | 瑞辰星生物技术（广州）有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119980752-A | Papermaking method for improving paper strength | 瑞辰星生物技术（广州）有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119555859-A | High-sensitivity high-flux identification method for saccharide compounds based on chlorine enhanced ionization | 北京大学 | 2025-03-04 | — | — | CN | claimed |
| CN-119505075-A | Phase permeability improver, fracturing fluid system containing same, and preparation method and application of phase permeability improver and fracturing fluid system | 中国石油天然气股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-116715868-B | Method for clean and efficient separation of acid hydrolysis fiber residue components and high-valued utilization of residual liquid | 北京林业大学 | 2025-02-14 | — | — | CN | claimed |
| CN-116041998-B | Super-hydrophilic coating composition, super-hydrophilic coating and preparation method thereof | 国家电投集团杭州新能源生产运营有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117625154-A | Polymer gel deep profile control agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-117629699-A | Papermaking method for improving paper strength | 瑞辰星生物技术（广州）有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-116715868-A | Method for clean and efficient separation of acid hydrolysis fiber residue components and high-valued utilization of residual liquid | 北京林业大学 | 2023-09-08 | — | — | CN | claimed |
| CN-116041998-A | Super-hydrophilic coating composition, super-hydrophilic coating and preparation method thereof | 国家电投集团杭州新能源生产运营有限公司 | 2023-05-02 | — | — | CN | claimed |
| WO-2005090422-A1 | PROCESS FOR PREPARING AN AQUEOUS DISPERSION OF A QUATERNARY AMMONIUM SALT CONTAINING VINYL COPOLYMER | BOSTIK, INC. (US) | 2005-09-29 | — | — | WO | claimed |
| EP-1539259-A1 | ION TRIGGERABLE, CATIONIC POLYMERS, A METHOD OF MAKING SAME AND ITEMS USING SAME | Kimberly-Clark Worldwide, Inc. (US) | 2005-06-15 | — | — | EP | claimed |
| EP-1539880-A1 | IMPROVED ION TRIGGERABLE, CATIONIC POLYMERS, A METHOD OF MAKING SAME AND ITEMS USING SAME | Kimberly-Clark Worldwide, Inc. (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004026352-A1 | USE AS BINDER OF ION TRIGGERABLE, VINYL-BASED CATIONIC POLYMERS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026351-A2 | IMPROVED ION TRIGGERABLE, CATIONIC POLYMERS, A METHOD OF MAKING SAME AND ITEMS USING SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026354-A1 | ION TRIGGERABLE, CATIONIC POLYMERS, A METHOD OF MAKING SAME AND ITEMS USING SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026958-A1 | IMPROVED ION TRIGGERABLE, CATIONIC POLYMERS, A METHOD OF MAKING SAME AND ITEMS USING SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2004-04-01 | — | — | WO | claimed |
| US-20040062791-A1 | Ion triggerable, cationic polymers, a method of making same and items using same | KIMBERLY-CLARK WORLDWIDE, INC. | 2004-04-01 | — | — | US | claimed |
| US-20040058606-A1 | Ion triggerable, cationic polymers, a method of making same and items using same | KIMBERLY-CLARK WORLDWIDE, INC. | 2004-03-25 | — | — | US | claimed |
| US-20040055704-A1 | Ion triggerable, cationic polymers, a method of making same and items using same | KIMBERLY-CLARK WORLDWIDE, INC. | 2004-03-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040062791-A1 | Ion triggerable, cationic polymers, a method of making same and items using same | PWWP2B, DSG1, WDR1 | GAA 3506/4885DPP4 4489/4885HTR1A 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.