Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6340252 | 0.83 | KMT2A (0.61) | ALDH1A1KMT2AMEN1POLBTHRB | |
| SCHEMBL3953437 | 0.82 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1POLBTHRB | |
| SCHEMBL156257 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1POLBTHRB | |
| SCHEMBL11311905 | 0.79 | KMT2A (0.60) | ALDH1A1KMT2AMEN1POLBTHRB | |
| SCHEMBL27553288 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1POLBTHRB | |
| Zinc Ion SCHEMBL9364014 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1POLBTHRB | |
| SCHEMBL11697583 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KMT2AALOX15CES2CES1 | |
| SCHEMBL181841 | 0.79 | ALDH1A1 (0.74) | ALDH1A1KMT2AMEN1POLBTHRB | |
| SCHEMBL8437671 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1POLBTHRB | |
| SCHEMBL29029980 | 0.77 | KMT2A (0.85) | ALDH1A1KMT2AMEN1POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592467-B2 | Inhibitors of prolyl endopeptidase | PROBIODRUG AG (DE) | 2009-09-22 | — | — | US | disclosed |
| US-20060229357-A1 | Compounds | PROBIODRUG AG | 2006-10-12 | — | — | US | disclosed |
| EP-0534443-B1 | 3,6-Disubstituted pyridazine derivatives | MITSUBISHI CHEM CORP (JP) | 1998-12-30 | — | — | EP | disclosed |
| US-5462941-A | 1-(cyclohexylalkylamino)-4-(phenyl, thienyl, or furyl) phthalazines; anti-platelet agglutination agents for treatment or prevention of cerebro- or cardiovascular disorders | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0575425-B1 | USE OF OXAZOLO- 2,3-a]ISOINDOLE AND IMIDAZO 2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO 2,3-a]ISOINDOLE DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1995-10-11 | — | — | EP | disclosed |
| EP-0569457-B1 | USE OF THIAZOLO-[2,3-A]ISOINDOLE DERIVATIVES AS ANTIVIRAL MEDICAMENTS AND NOVEL THIAZOLO- [2,3-A]ISOINDOLE DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0575425-A1 | USE OF OXAZOLO- 2,3-a]ISOINDOLE AND IMIDAZO 2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO 2,3-a]ISOINDOLE DERIVATIVES. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0534443-A1 | 3,6-Disubstituted pyridazine derivatives | Mitsubishi Chemical Corporation (JP) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992016207-A1 | USE OF OXAZOLO-[2,3-a]ISOINDOLE AND IMIDAZO[2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO[2,3-a]ISOINDOLE DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |
| US-3994920-A | APPETITE SUPPRESSANT, ANTIDEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229357-A1 | Compounds | PREP, BACE1, MME | ALDH1A1 2334/4885KMT2A 1173/4885MEN1 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.