Iocarmic Acid

Iocarmic Acid

SCHEMBL38580

CNC(=O)c1c(I)c(NC(=O)CCCCC(=O)Nc2c(I)c(C(=O)O)c(I)c(C(=O)NC)c2I)c(I)c(C(=O)O)c1I

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
MAPK1 P28482 1/20 0.56
LMNA P02545 4/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
HDAC1 Q13547 9/20 0.38
HDAC11 Q96DB2 7/20 0.38
HDAC8 Q9BY41 7/20 0.38
HDAC6 Q9UBN7 7/20 0.38
HDAC2 Q92769 7/20 0.38
HDAC4 P56524 6/20 0.38
HDAC7 Q8WUI4 6/20 0.38
HDAC9 Q9UKV0 6/20 0.38
HDAC5 Q9UQL6 6/20 0.38
HDAC3 O15379 6/20 0.38
HDAC10 Q969S8 6/20 0.38
NCOR2 Q9Y618 2/20 0.33
KDM4E B2RXH2 1/20 0.33
BRD4 O60885 1/20 0.33
NCOR1 O75376 1/20 0.33
NR1I2 O75469 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iosefamic Acid SCHEMBL38639 0.98 TSHR (0.55) TSHRMAPK1LMNASMN1; SMN2HDAC1
Iosefamic Acid SCHEMBL29648519 0.98 TSHR (0.55) TSHRMAPK1LMNASMN1; SMN2HDAC1
Iosefamic Acid SCHEMBL29400390 0.98 TSHR (0.55) TSHRMAPK1LMNASMN1; SMN2HDAC1
SCHEMBL8610051 0.86 LMNA (0.42) TSHRMAPK1LMNASMN1; SMN2
SCHEMBL30881052 0.86 LMNA (0.42) TSHRMAPK1LMNASMN1; SMN2KDM4E
SCHEMBL11632856 0.85 MAPK1 (0.46) TSHRMAPK1SMN1; SMN2MEN1KMT2A
SCHEMBL9716687 0.84 TSHR (0.52) TSHRMAPK1LMNASMN1; SMN2HDAC1
Iocarmic Acid SCHEMBL29886627 0.84 SMN1; SMN2 (0.65) TSHRMAPK1LMNASMN1; SMN2KDM4E
SCHEMBL3833534 0.84 LMNA (0.40) TSHRMAPK1LMNASMN1; SMN2CYP3A4
SCHEMBL11406813 0.82 LMNA (0.47) TSHRMAPK1LMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683579-A1 RELIEVE BACK PAIN AND/OR REBUILDING INTERVERTERAL DISC Yeung, Jeffrey E. (US) 2026-01-28 EP claimed
US-20250170279-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2025-05-29 US claimed
US-20250170280-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2025-05-29 US claimed
WO-2024158529-A1 RELIEVE BACK PAIN AND/OR REBUILDING INTERVERTERAL DISC YEUNG JEFFREY E (US) 2024-08-02 WO claimed
WO-2021238893-A1 EFFICIENT AND EFFECTIVE TISSUE CLEARING AGENTS AND THEIR COMPOSITIONS THE CHINESE UNIVERSITY OF HONG KONG (CN) 2021-12-02 WO claimed
US-20210145747-A1 CERASOME DELIVERY SYSTEM FOR TARGETING ACTIVATED CD44 MOLECULE, PREPARATION METHOD AND USE THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2021-05-20 US claimed
CN-110402137-B Silica body delivery system for targeted activation of CD44 molecule, and preparation method and application thereof 北京茵诺医药科技有限公司 2021-03-09 CN claimed
CN-110545799-B Recombinant bionic nano-carrier delivery system for targeting activation of CD44 molecule, and preparation method and application thereof 北京茵诺医药科技有限公司 2021-02-26 CN claimed
CN-110545800-B Nano-calcium carrier delivery system for targeting activation of CD44 molecule, and preparation method and application thereof 北京茵诺医药科技有限公司 2021-02-26 CN claimed
CN-110545793-B Metal framework compound nano-carrier delivery system for targeting activation of CD44 molecule, preparation method and application thereof 北京茵诺医药科技有限公司 2021-02-26 CN claimed
JP-2691073-B2 1997-12-17 JP claimed
US-5660814-A Iodinated paramagnetic chelates, and their use as contrast agents DIBRA S.P.A. (IT) 1997-08-26 US claimed
EP-0767779-A1 ALPHA-(CYCLOALKYL, ARYL AND ARALKYL)SUBSTITUTED POLYIODINATED AROYLOXY COMPOUNDS NanoSystems L.L.C. (US) 1997-04-16 EP claimed
EP-0703790-A1 IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS BRACCO S.p.A. (IT) 1996-04-03 EP claimed
WO-1996000211-A1 ALPHA-(CYCLOALKYL, ARYL AND ARALKYL)SUBSTITUTED POLYIODINATED AROYLOXY COMPOUNDS NANOSYSTEMS L.L.C. (US) 1996-01-04 WO claimed
EP-0644740-A4 STEREOTACTIC MAMMOGRAPHY AND NEEDLE BIOPSY TABLE WITH CCD IMAGING SYSTEM. THERMOTREX CORP LORAD CORP (US) 1995-11-02 EP claimed
EP-0644740-A1 STEREOTACTIC MAMMOGRAPHY AND NEEDLE BIOPSY TABLE WITH CCD IMAGING SYSTEM THERMOTREX CORPORATION (US) 1995-03-29 EP claimed
WO-1994027644-A1 IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS BRACCO S.P.A. (IT) 1994-12-08 WO claimed
WO-1993011706-A1 STEREOTACTIC MAMMOGRAPHY AND NEEDLE BIOPSY TABLE WITH CCD IMAGING SYSTEM PELLEGRINO ANTHONY J (US) 1993-06-24 WO claimed
EP-0050457-A1 Radiopaque cyanoacrylate compositions BioNexus, Inc. (US) 1982-04-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210145747-A1 CERASOME DELIVERY SYSTEM FOR TARGETING ACTIVATED CD44 MOLECULE, PREPARATION METHOD AND USE THEREOF CD44, LDLR, PLAUR TSHR 3170/4885MAPK1 3939/4885LMNA 265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.