⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666084 | 0.82 | — | — | |
| Ethylene SCHEMBL1115912 | 0.78 | TSHR (0.33) | — | |
| Ethylene SCHEMBL1065214 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL4399476 | 0.77 | TSHR (0.30) | — | |
| SCHEMBL1108998 | 0.77 | — | — | |
| SCHEMBL23928729 | 0.76 | — | — | |
| SCHEMBL844249 | 0.74 | MEN1 (0.55) | — | |
| SCHEMBL394606 | 0.74 | DNM1 (0.40) | — | |
| SCHEMBL9056856 | 0.74 | MEN1 (0.55) | — | |
| Butane SCHEMBL7846373 | 0.74 | ADRB2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934239-A4 | IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE | IDERA PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1934239-A2 | IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE | Idera Pharmaceuticals, Inc. (US) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007047396-A2 | IMMUNE REGULATORY OLIGONUCLEOTIDE (IRO) COMPOUNDS TO MODULATE TOLL-LIKE RECEPTOR BASED IMMUNE RESPONSE | IDERA PHARMACEUTICALS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |