SCHEMBL3858215

SCHEMBL3858215

Cc1sc2cc([N+](=O)[O-])ccc2c1C1=C(c2c(C)sc3cc([N+](=O)[O-])ccc23)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ HTT P42858 1/20 0.42
▸ ALDH1A1 P00352 9/20 0.39
▸ MAPT P10636 6/20 0.39
▸ HPGD P15428 4/20 0.39
▸ USP2 O75604 1/20 0.39
▸ TDP1 Q9NUW8 3/20 0.37
▸ TSHR P16473 3/20 0.37
▸ CRHBP P24387 1/20 0.37
▸ CRHR2 Q13324 1/20 0.37
▸ HK1 P19367 1/20 0.36
▸ HKDC1 Q2TB90 1/20 0.36
▸ APOBEC3G Q9HC16 1/20 0.36
▸ CYP3A4 P08684 3/20 0.36
▸ PDK1 Q15118 1/20 0.35
▸ PHOSPHO1 Q8TCT1 1/20 0.35
▸ KMT2A Q03164 2/20 0.34
▸ INSR P06213 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31736137 1.00 SMN1; SMN2 (0.42) SMN1; SMN2HTTALDH1A1MAPTHPGD
SCHEMBL1041361 0.93 SMN1; SMN2 (0.39) SMN1; SMN2HTTALDH1A1MAPTHPGD
SCHEMBL3859690 0.90 MAPT (0.43) SMN1; SMN2HTTALDH1A1MAPTTDP1
SCHEMBL5501887 0.83 SMN1; SMN2 (0.39) SMN1; SMN2HTTALDH1A1MAPTHPGD
SCHEMBL20527904 0.79 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MAPTHPGD
SCHEMBL19361388 0.79 BCL2L1 (0.36) MAPT
SCHEMBL13730638 0.75 SMN1; SMN2 (0.51) SMN1; SMN2HTTALDH1A1MAPTHPGD
SCHEMBL5501890 0.73 SMN1; SMN2 (0.36) SMN1; SMN2HTTALDH1A1MAPTHPGD
SCHEMBL749155 0.71 CRHBP (0.53) SMN1; SMN2HTTALDH1A1MAPTHPGD
SCHEMBL6498933 0.71 PLA2G10 (0.37) SMN1; SMN2ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3732533-B1 SYSTEM AND METHOD FOR CUSTOMIZATION OF A PHOTOCHROMIC ARTICLE TRANSITIONS OPTICAL LTD (IE) 2025-12-10 — — EP disclosed
US-11609442-B2 System and method for customization of a photochromic article TRANSITIONS OPTICAL, LTD. (IE) 2023-03-21 — — US disclosed
US-20210055575-A1 System and Method for Customization of a Photochromic Article TRANSITIONS OPTICAL, LTD. (IE) 2021-02-25 — — US disclosed
US-20140249050-A1 METHOD AND DEVICE FOR THE MANIPULATION OF MICROCARRIERS FOR AN IDENTIFICATION PURPOSE BIOCARTIS SA (CH) 2014-09-04 — — US disclosed
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 — — US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 — — US disclosed
EP-1637570-B1 Color-memorizing photochromic writing instrument PILOT INK CO LTD (JP) 2007-06-27 — — EP disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 — — US disclosed
EP-1637570-A1 Color-memorizing photochromic writing instrument THE PILOT INK CO., LTD. (JP) 2006-03-22 — — EP disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 — — US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 — — EP disclosed
US-20040135097-A1 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. 2004-07-15 — — US disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 — — EP disclosed
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