SCHEMBL3859690

SCHEMBL3859690

Cc1sc2ccc([N+](=O)[O-])cc2c1C1=C(c2c(C)sc3ccc([N+](=O)[O-])cc23)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.43
▸ ALDH1A1 P00352 4/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ POLB P06746 2/20 0.39
▸ HTT P42858 1/20 0.39
▸ MCL1 Q07820 2/20 0.38
▸ AHR P35869 1/20 0.38
▸ SAE1 Q9UBE0 1/20 0.38
▸ UBA2 Q9UBT2 1/20 0.38
▸ TDP1 Q9NUW8 2/20 0.37
▸ TSHR P16473 2/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ PKM P14618 1/20 0.36
▸ NPY1R P25929 1/20 0.36
▸ NPY2R P49146 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ CYP3A4 P08684 2/20 0.36
▸ EGFR P00533 1/20 0.35
▸ G6PD P11413 1/20 0.35
▸ TLR9 Q9NR96 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31736137 0.90 SMN1; SMN2 (0.42) MAPTALDH1A1SMN1; SMN2POLBHTT
SCHEMBL3858215 0.90 SMN1; SMN2 (0.42) MAPTALDH1A1SMN1; SMN2POLBHTT
SCHEMBL1041361 0.83 SMN1; SMN2 (0.39) MAPTALDH1A1SMN1; SMN2HTTTDP1
SCHEMBL5501889 0.83 MAPT (0.40) MAPTALDH1A1SMN1; SMN2POLBHTT
SCHEMBL23612353 0.73 MAPT (0.46) MAPTALDH1A1SMN1; SMN2POLBHTT
SCHEMBL30061649 0.73 MAPT (0.46) MAPTALDH1A1SMN1; SMN2POLBHTT
SCHEMBL5501887 0.73 SMN1; SMN2 (0.39) MAPTALDH1A1SMN1; SMN2HTTTDP1
SCHEMBL11118149 0.71 SMN1; SMN2 (0.50) MAPTALDH1A1SMN1; SMN2POLBHTT
SCHEMBL20527904 0.71 SMN1; SMN2 (0.40) MAPTALDH1A1SMN1; SMN2
SCHEMBL5501890 0.68 SMN1; SMN2 (0.36) MAPTALDH1A1SMN1; SMN2POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3732533-B1 SYSTEM AND METHOD FOR CUSTOMIZATION OF A PHOTOCHROMIC ARTICLE TRANSITIONS OPTICAL LTD (IE) 2025-12-10 — — EP disclosed
US-11609442-B2 System and method for customization of a photochromic article TRANSITIONS OPTICAL, LTD. (IE) 2023-03-21 — — US disclosed
US-20210055575-A1 System and Method for Customization of a Photochromic Article TRANSITIONS OPTICAL, LTD. (IE) 2021-02-25 — — US disclosed
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 — — US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 — — US disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 — — US disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 — — US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 — — EP disclosed
US-20040135097-A1 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. 2004-07-15 — — US disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 — — EP disclosed
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