Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3858215 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTALDH1A1TDP1TSHR | |
| SCHEMBL31736137 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTALDH1A1TDP1TSHR | |
| SCHEMBL1041361 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2HTTALDH1A1TDP1TSHR | |
| SCHEMBL3859690 | 0.68 | MAPT (0.43) | SMN1; SMN2HTTALDH1A1TDP1TSHR | |
| SCHEMBL25221160 | 0.68 | PHOSPHO1 (0.43) | SMN1; SMN2HTTALDH1A1TDP1TSHR | |
| SCHEMBL2843783 | 0.66 | ALDH1A1 (0.51) | SMN1; SMN2HTTALDH1A1TDP1CYP3A4 | |
| SCHEMBL11948485 | 0.65 | KMT2A (0.53) | SMN1; SMN2ALDH1A1TDP1TSHRCYP1A2 | |
| SCHEMBL2842217 | 0.65 | NPC1 (0.46) | SMN1; SMN2ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL10373575 | 0.65 | CYP2A6 (0.50) | SMN1; SMN2HTTALDH1A1TDP1TSHR | |
| SCHEMBL5338932 | 0.64 | ALDH1A1 (0.52) | SMN1; SMN2HTTALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637570-B1 | Color-memorizing photochromic writing instrument | PILOT INK CO LTD (JP) | 2007-06-27 | — | — | EP | disclosed |
| EP-1637570-A1 | Color-memorizing photochromic writing instrument | THE PILOT INK CO., LTD. (JP) | 2006-03-22 | — | — | EP | disclosed |