Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910884 | 1.00 | IDO1 (0.50) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL477718 | 1.00 | IDO1 (0.50) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL30986701 | 1.00 | IDO1 (0.50) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL30910940 | 0.87 | CES2 (0.43) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL30986702 | 0.87 | CES2 (0.43) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL6566037 | 0.87 | CES2 (0.43) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL30057873 | 0.85 | CES2 (0.52) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL1902230 | 0.85 | CES2 (0.52) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL21831230 | 0.85 | CES2 (0.47) | IDO1TDO2GAAMEN1KMT2A | |
| SCHEMBL30910879 | 0.85 | CES2 (0.47) | IDO1TDO2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592487-B2 | Chiral tertiary aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-09-22 | — | — | US | disclosed |
| US-7592487-B2 | Chiral tertiary aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-09-22 | — | — | US | disclosed |
| US-7592487-B2 | Chiral tertiary aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-09-22 | — | — | US | disclosed |
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2008-02-21 | — | — | US | disclosed |
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2008-02-21 | — | — | US | disclosed |
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2008-02-21 | — | — | US | disclosed |
| CN-1930116-A | Chiral tertiary aminoalkylnaphthols | UNIV HONG KONG POLYTECHNIC (HK) | 2007-03-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | ALDH7A1, ADH5, ALDH1A1 | IDO1 515/4885TDO2 268/4885GAA 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.