Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 7/20 | 0.94 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5091656 | 1.00 | DNM1 (0.94) | DNM1TSHRTHRBLMNABDKRB2 | |
| Iodide SCHEMBL5088416 | 1.00 | DNM1 (0.94) | DNM1TSHRTHRBLMNABDKRB2 | |
| Iodide SCHEMBL5085198 | 1.00 | DNM1 (0.94) | DNM1TSHRTHRBLMNABDKRB2 | |
| Iodide SCHEMBL5091864 | 1.00 | DNM1 (0.94) | DNM1TSHRTHRBLMNABDKRB2 | |
| Iodide SCHEMBL5087203 | 1.00 | DNM1 (0.94) | DNM1TSHRTHRBLMNABDKRB2 | |
| Iodide SCHEMBL5087043 | 1.00 | DNM1 (0.94) | DNM1TSHRTHRBLMNABDKRB2 | |
| Iodide SCHEMBL5086658 | 1.00 | DNM1 (0.94) | DNM1TSHRTHRBLMNABDKRB2 | |
| Iodide SCHEMBL5088125 | 1.00 | DNM1 (0.94) | DNM1TSHRTHRBLMNABDKRB2 | |
| Iodide SCHEMBL5085433 | 1.00 | DNM1 (0.94) | DNM1TSHRTHRBLMNABDKRB2 | |
| Iodide SCHEMBL5091621 | 1.00 | DNM1 (0.94) | DNM1TSHRTHRBLMNABDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238606-B1 | Methyl-Iodide-free carbonylation of methanol to acetaldehyde | EASTMAN CHEMICAL COMPANY (US) | 2016-01-19 | — | — | US | claimed |
| EP-1501779-B1 | CONTINUOUS CARBONYLATION PROCESS | EASTMAN CHEM CO (US) | 2009-12-23 | — | — | EP | claimed |
| EP-1501779-A1 | CONTINUOUS CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093211-A1 | CONTINUOUS CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2003-11-13 | — | — | WO | claimed |
| US-20030212295-A1 | Continuous carbonylation process | EASTMAN CHEMICAL COMPANY | 2003-11-13 | — | — | US | claimed |
| US-6395912-B1 | ISOMERIZATION OF EPOXY COMPOUND | EASTMAN CHEMICAL COMPANY | 2002-05-28 | — | — | US | claimed |
| US-6342614-B1 | ISOMERIZATION OF GAMMA, DELTA-EPOXYALKENES OR GAMMA, DELTA-EPOXYCYCLOALKENES TO 2,5-DIHYDROFURANS USING CATALYTIC SYSTEM WHICH COMPRISES ONIUM IODIDE AND LEWIS ACID | EASTMAN CHEMICAL COMPANY | 2002-01-29 | — | — | US | claimed |
| US-9266807-B1 | Conversion of alcohols to longer chain aldehydes or alcohols | EASTMAN CHEMICAL COMPANY (US) | 2016-02-23 | — | — | US | disclosed |
| US-9238606-B1 | Methyl-Iodide-free carbonylation of methanol to acetaldehyde | EASTMAN CHEMICAL COMPANY (US) | 2016-01-19 | — | — | US | disclosed |
| EP-1501779-B1 | CONTINUOUS CARBONYLATION PROCESS | EASTMAN CHEM CO (US) | 2009-12-23 | — | — | EP | disclosed |
| US-7629491-B2 | Hydrocarboxylation process | EASTMAN CHEMICAL COMPANY (US) | 2009-12-08 | — | — | US | disclosed |
| WO-2009123675-A1 | IMPROVED CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2009-10-08 | — | — | WO | disclosed |
| US-20090247783-A1 | CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2009-10-01 | — | — | US | disclosed |
| US-7582792-B2 | Carbonylation process | EASTMAN CHEMICAL COMPANY (US) | 2009-09-01 | — | — | US | disclosed |
| US-20070299280-A1 | forming propionic acid from ethylene, water and carbon monoxide; not using the hazardous and corrosive hydrogen halides or sulfonic acids; free of hydrogen iodide and/or ethyl iodide; no diethyl ketone by-products | EASTMAN CHEMICAL COMPANY (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070293695-A1 | CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2007-12-20 | — | — | US | disclosed |
| US-6916951-B2 | Continuous carbonylation process | EASTMAN CHEMICAL COMPANY (US) | 2005-07-12 | — | — | US | disclosed |
| EP-1501779-A1 | CONTINUOUS CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093211-A1 | CONTINUOUS CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2003-11-13 | — | — | WO | disclosed |
| US-20030212295-A1 | Continuous carbonylation process | EASTMAN CHEMICAL COMPANY | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293695-A1 | CARBONYLATION PROCESS | CBR3, HAO2, CA4 | DNM1 3533/4885TSHR 1538/4885THRB 1030/4885 |
| US-20070299280-A1 | forming propionic acid from ethylene, water and carbon monoxide; not using the hazardous and corrosive hydrogen halides or sulfonic acids; free of hydrogen iodide and/or ethyl iodide; no diethyl ketone by-products | ETV6, ETV1, HAO2 | DNM1 985/4885TSHR 2619/4885THRB 1693/4885 |
| US-20090247783-A1 | CARBONYLATION PROCESS | CA4, HAO2, CA9 | DNM1 2159/4885TSHR 1657/4885THRB 1556/4885 |
| US-20030212295-A1 | Continuous carbonylation process | CA4, CA5B, CA14 | DNM1 2851/4885TSHR 4418/4885THRB 4711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.