Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.72 |
| ▸ | RAB9A | P51151 | 12/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.72 |
| ▸ | TP53 | P04637 | 5/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | NQO2 | P16083 | 1/20 | 0.69 |
| ▸ | CASP3 | P42574 | 4/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.66 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.66 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.66 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917029 | 0.90 | NPC1 (0.82) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL28937078 | 0.85 | TOP1 (0.74) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL8398096 | 0.85 | RAB9A (0.86) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL5399964 | 0.85 | RAB9A (0.86) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL3869333 | 0.85 | KMT2A (0.68) | NPC1RAB9ASMN1; SMN2TP53NQO2 | |
| SCHEMBL18063675 | 0.85 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL6799157 | 0.84 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL16675165 | 0.83 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL16675159 | 0.83 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL715515 | 0.82 | NQO2 (1.00) | NPC1RAB9ATP53NQO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915337-A4 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORP (KR) | 2009-04-22 | — | — | EP | disclosed |
| US-20080280989-A1 | Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same | AMOREPACIFIC CORPORATION (KR) | 2008-11-13 | — | — | US | disclosed |
| EP-1915337-A1 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | Amorepacific Corporation (KR) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007021067-A1 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280989-A1 | Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same | H1-0, HAAO, H1-10 | NPC1 4272/4885RAB9A 2523/4885SMN1; SMN2 2739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.