SCHEMBL2917029

SCHEMBL2917029

COc1ccc(NC(=O)c2cc(C(=O)Nc3ccc(OC)cc3)cc(C(=O)Nc3ccc(OC)cc3)c2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 13/20 0.82
RAB9A P51151 12/20 0.82
SMN1; SMN2 Q16637 7/20 0.82
TP53 P04637 5/20 0.82
ALOX15 P16050 1/20 0.82
TAS1R3 Q7RTX0 1/20 0.73
TAS1R1 Q7RTX1 1/20 0.73
TAS1R2 Q8TE23 1/20 0.73
ALOX5 P09917 1/20 0.69
ALDH1A1 P00352 4/20 0.69
KMT2A Q03164 3/20 0.69
CYP1A2 P05177 2/20 0.69
MEN1 O00255 2/20 0.69
GAA P10253 2/20 0.69
CYP3A4 P08684 1/20 0.69
CYP2D6 P10635 1/20 0.69
CYP2C9 P11712 1/20 0.69
CYP2C19 P33261 1/20 0.69
CASP3 P42574 2/20 0.69
SENP7 Q9BQF6 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16675165 0.93 NPC1 (0.83) NPC1RAB9ASMN1; SMN2TP53ALOX15
SCHEMBL15413191 0.91 NPC1 (0.78) NPC1RAB9ASMN1; SMN2TP53ALOX15
SCHEMBL6799157 0.90 RAB9A (1.00) NPC1RAB9ASMN1; SMN2TP53ALOX15
SCHEMBL14130400 0.90 NPC1 (0.68) NPC1RAB9ASMN1; SMN2TP53ALOX15
SCHEMBL16675159 0.90 NPC1 (0.83) NPC1RAB9ASMN1; SMN2TP53ALOX15
SCHEMBL3860243 0.90 NPC1 (0.72) NPC1RAB9ASMN1; SMN2TP53ALOX15
SCHEMBL28937078 0.88 TOP1 (0.74) NPC1RAB9ASMN1; SMN2TP53ALOX15
SCHEMBL9190681 0.87 ABCB1 (0.76) NPC1RAB9ASMN1; SMN2TP53ALOX15
SCHEMBL24441524 0.85 NPC1 (0.76) NPC1RAB9ASMN1; SMN2TP53ALOX15
SCHEMBL704563 0.85 TAS1R3 (1.00) NPC1RAB9ASMN1; SMN2TP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732198-B2 Mono- and multi-layer blown films BASF SE (DE) 2017-08-15 US disclosed
US-20170081486-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2017-03-23 US disclosed
WO-2016190105-A1 POLYIMIDE FILM, METHOD FOR PRODUCING POLYIMIDE FILM, FLEXIBLE PRINTED BOARD, SUBSTRATE FOR FLEXIBLE DISPLAYS, FRONT PLATE FOR FLEXIBLE DISPLAYS, LED LIGHTING DEVICE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE コニカミノルタ株式会社 2016-12-01 WO disclosed
US-20160136871-A1 Mono- and Multi-Layer Blown Films BASF SE (DE) 2016-05-19 US disclosed
US-9278487-B2 Mono-and multi-layer blown films BASF SE (DE) 2016-03-08 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20130161875-A1 MONO-AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2013-06-27 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed
EP-2026965-B1 MONO- AND MULTI-LAYER BLOWN FILMS BASF SE (DE) 2010-09-01 EP disclosed
US-20090208718-A1 Mono-and multi-layer blown films CIBA CORP. 2009-08-20 US disclosed
US-7479515-B2 Polypropylene resin compositions CIBA SPECIALTY CHEMICALS CORP. (US) 2009-01-20 US disclosed
US-20070170398-A1 Polypropylene resin compositions SCHMIDT HANS-WERNER 2007-07-26 US disclosed
US-7235191-B2 Crystallizable polypropylene homopolymer, random copolymer, alternating or segmented copolymer, block copolymer or a blend of polypropylene with another synthetic polymer, and b) 0.001 to 5% relative to the weight of component (a), of a specific CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 US disclosed
EP-1366116-B1 POLYPROPYLENE RESIN COMPOSITIONS CIBA SC HOLDING AG (CH) 2006-07-19 EP disclosed
US-20040063830-A1 Crystallizable polypropylene homopolymer, random copolymer, alternating or segmented copolymer, block copolymer or a blend of polypropylene with another synthetic polymer, and b) 0.001 to 5% relative to the weight of component (a), of a specific CIBA SPECIALTY CHEMICALS CORPORATION 2004-04-01 US disclosed