SCHEMBL715515

SCHEMBL715515

O=C(Nc1ccc(O)cc1)c1cc(O)cc(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 2/20 1.00
SNCA P37840 4/20 0.68
DEGS1 O15121 4/20 0.64
TOP1 P11387 2/20 0.62
TOP2A P11388 1/20 0.62
TOP2B Q02880 1/20 0.62
NPC1 O15118 1/20 0.59
TP53 P04637 1/20 0.59
RAB9A P51151 1/20 0.59
PEPD P12955 1/20 0.52
MEN1 O00255 1/20 0.52
CA12 O43570 1/20 0.52
BRD4 O60885 1/20 0.52
NR1I2 O75469 1/20 0.52
ALDH1A1 P00352 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
MB P02144 1/20 0.52
CYP1A1 P04798 1/20 0.52
CA3 P07451 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16677959 0.91 NQO2 (0.84) NQO2SNCADEGS1TOP1TOP2A
SCHEMBL18063650 0.90 NQO2 (0.81) NQO2SNCADEGS1TOP1TOP2A
SCHEMBL11154646 0.86 NQO2 (0.76) NQO2SNCADEGS1TOP1TOP2A
SCHEMBL14008035 0.86 NQO2 (0.76) NQO2SNCATOP1TOP2ATOP2B
SCHEMBL4740949 0.86 NQO2 (0.75) NQO2DEGS1TOP1TOP2ATOP2B
SCHEMBL8420639 0.85 DEGS1 (0.75) NQO2SNCADEGS1TOP1NPC1
SCHEMBL899585 0.85 DEGS1 (0.75) NQO2SNCADEGS1TOP1NPC1
SCHEMBL900928 0.85 DEGS1 (0.75) NQO2SNCADEGS1TOP1NPC1
SCHEMBL6027801 0.83 NQO2 (1.00) NQO2SNCADEGS1TOP1NPC1
SCHEMBL28661358 0.83 NQO2 (0.70) NQO2SNCADEGS1TOP1TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2020-06-18 US claimed
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-10-06 US claimed
EP-2391658-B1 MOLECULARLY IMPRINTED POLYMERS COMMW SCIENT IND RES ORG (AU) 2015-09-23 EP claimed
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2012-03-01 US claimed
EP-2391658-A1 MOLECULARLY IMPRINTED POLYMERS Commonwealth Scientific and Industrial Research Organisation (AU) 2011-12-07 EP claimed
WO-2010085851-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-08-05 WO claimed
CN-115160540-B High-modulus high-activity epoxy resin and synthetic method and application thereof 四川大学 2024-01-26 CN disclosed
CN-115181246-A High-strength high-modulus epoxy resin and synthesis method and application thereof 四川大学 2022-10-14 CN disclosed
CN-115160540-A High-modulus high-activity epoxy resin and synthesis method and application thereof 四川大学 2022-10-11 CN disclosed
CN-115160734-A High-strength high-modulus Schiff base epoxy resin, carbon fiber composite material and application thereof 四川大学 2022-10-11 CN disclosed
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2020-06-18 US disclosed
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2020-06-18 US disclosed
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-10-06 US disclosed
WO-2010085851-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-08-05 WO disclosed
WO-2010085851-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-08-05 WO disclosed
EP-1915337-A4 HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME AMOREPACIFIC CORP (KR) 2009-04-22 EP disclosed
US-20080280989-A1 Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same AMOREPACIFIC CORPORATION (KR) 2008-11-13 US disclosed
CN-101243042-A Hydroxybenzamide derivatives, the method for preparing thereof and the cosmetic composition containing the same AMOREPACIFIC CORP (KR) 2008-08-13 CN disclosed
EP-1915337-A1 HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME Amorepacific Corporation (KR) 2008-04-30 EP disclosed
WO-2007021067-A1 HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME AMOREPACIFIC CORPORATION (KR) 2007-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 NQO2 2288/4885SNCA 4492/4885DEGS1 4552/4885
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 NQO2 2288/4885SNCA 4492/4885DEGS1 4552/4885
US-20080280989-A1 Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same H1-0, HAAO, H1-10 NQO2 413/4885SNCA 569/4885DEGS1 728/4885
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 NQO2 2288/4885SNCA 4492/4885DEGS1 4552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.