Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | FER | P16591 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31013336 | 0.71 | GABRA1 (0.46) | GABRA1GABRB2GAAMAPT | |
| SCHEMBL21650259 | 0.70 | LMNA (0.34) | GABRA1GABRB2 | |
| SCHEMBL16746136 | 0.69 | XIAP (0.36) | — | |
| SCHEMBL16746087 | 0.69 | XIAP (0.33) | — | |
| SCHEMBL16746085 | 0.68 | ADRA2A (0.33) | — | |
| SCHEMBL1292825 | 0.67 | GABRA1 (0.41) | GABRA1GABRB2 | |
| SCHEMBL2023542 | 0.64 | ACVR1 (0.39) | ACVR1LRRK2ROS1CDK5PDGFRA | |
| SCHEMBL624418 | 0.64 | GAA (0.59) | ACVR1LRRK2ROS1CDK5PDGFRA | |
| SCHEMBL29369547 | 0.64 | GAA (0.59) | ACVR1LRRK2ROS1CDK5PDGFRA | |
| SCHEMBL2676730 | 0.64 | GAA (0.59) | ACVR1LRRK2ROS1CDK5PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812822-A4 | ELECTROCHROMIC COMPOUNDS AND ASSOCIATED MEDIA AND DEVICES | GENTEX CORP (US) | 2009-04-15 | — | — | EP | disclosed |
| CN-101069124-A | Electrochromic compounds and related media and devices | GENTEX CORP (US) | 2007-11-07 | — | — | CN | disclosed |
| EP-1812822-A2 | ELECTROCHROMIC COMPOUNDS AND ASSOCIATED MEDIA AND DEVICES | Gentex Corporation (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006055391-A2 | ELECTROCHROMIC COMPOUNDS AND ASSOCIATED MEDIA AND DEVICES | GENTEX CORPORATION (US) | 2006-05-26 | — | — | WO | disclosed |