Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859086 | 0.79 | TDP1 (0.33) | TSHR | |
| SCHEMBL1493095 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL3422344 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL27730789 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL16767129 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL388507 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL10614948 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL30402501 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL10975862 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL143427 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592392-B2 | Synthesis of functional polymers for use in organic synthesis and combinatorial chemistry | MERCK & CO. INC. (US) | 2009-09-22 | — | — | US | disclosed |
| US-20060189764-A1 | Synthesis of functional polymers for use in organic synthesis and combinatorial chemistry | MERCK SHARP & DOHME CORP. | 2006-08-24 | — | — | US | disclosed |
| WO-2000078740-A1 | SOLID-SUPPORTED INITIATORS AND FUNCTIONAL POLYMERS FOR USE IN ORGANIC SYNTHESIS AND COMBINATORIAL CHEMISTRY | WARNER-LAMBERT COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |