SCHEMBL3422344

SCHEMBL3422344

C=Cc1ccccc1[SiH](CC)CC

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10975862 0.79 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL6114181 0.77 TP53 (0.36) TSHRLMNA
SCHEMBL1493095 0.76 ALDH1A1 (0.44) ALDH1A1TSHRLMNA
SCHEMBL3861883 0.75 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL812109 0.75 ALDH1A1 (0.36) ALDH1A1
SCHEMBL31468480 0.72
SCHEMBL31468470 0.72
SCHEMBL16767129 0.72 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL28730873 0.72 GABRA1 (0.40) ALDH1A1TSHRLMNA
SCHEMBL31468519 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103819593-A Hydrosilicon functionalized rare earth syndiotactic polystyrene and preparation method UNIV DALIAN TECH 2014-05-28 CN claimed
CN-103819593-A Hydrosilicon functionalized rare earth syndiotactic polystyrene and preparation method UNIV DALIAN TECH 2014-05-28 CN disclosed
EP-2138525-B1 EPOXY SILICONE AND METHOD FOR PRODUCTION THEREOF, AND CURABLE RESIN COMPOSITION USING THE SAME AND USE THEREOF ASAHI KASEI CHEMICALS CORP (JP) 2012-12-26 EP disclosed
US-8222348-B2 Epoxy silicone and process for producing same, and curable mix composition using same and use thereof ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-07-17 US disclosed
CN-101657490-B Epoxy silicone, method for producing same, curable resin composition using same, and use thereof ASAHI KASEI CHEMICALS CORP (JP) 2012-07-04 CN disclosed
US-20100120975-A1 EPOXY SILICONE AND PROCESS FOR PRODUCING SAME, AND CURABLE MIX COMPOSITION USING SAME AND USE THEREOF ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-05-13 US disclosed
CN-101657490-A Epoxy silicone, method for producing same, curable resin composition using same, and use thereof ASAHI CHEMICAL CORP (JP) 2010-02-24 CN disclosed
EP-2138525-A1 EPOXY SILICONE AND METHOD FOR PRODUCTION THEREOF, AND CURABLE RESIN COMPOSITION USING THE SAME AND USE THEREOF Asahi Kasei Chemicals Corporation (JP) 2009-12-30 EP disclosed