Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | GPR3 | P46089 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241035 | 0.69 | GAA (0.40) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL3353907 | 0.68 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL6665978 | 0.62 | PBRM1 (0.49) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL5776544 | 0.60 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL15616167 | 0.60 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL555502 | 0.59 | CYP1A2 (0.44) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL1376166 | 0.58 | ALDH1A1 (0.48) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL6437053 | 0.58 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL2499917 | 0.57 | CA1 (0.45) | KDM4EALDH1A1HPGDCYP1A2HSD17B10 | |
| SCHEMBL4146783 | 0.54 | ALDH1A1 (0.90) | KDM4EALDH1A1SMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576536-A2 | HAEMATOPOIETIC-PROSTAGLANDIN D2 SYNTHASE INHIBITORS | The University of Queensland (AU) | 2013-04-10 | — | — | EP | disclosed |
| WO-2012142659-A1 | SITE-SELECTIVE MODIFICATION OF PROTEINS | BAKER IDI HEART AND DIABETES INSTITUTE HOLDINGS LIMITED (AU) | 2012-10-26 | — | — | WO | disclosed |
| WO-2011150457-A2 | HAEMATOPOIETIC-PROSTAGLANDIN D2 SYNTHASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2011-12-08 | — | — | WO | disclosed |