SCHEMBL3864202

SCHEMBL3864202

C=Cc1cc(Br)c(O)c(Br)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TRPA1 O75762 1/20 0.50
LCK P06239 3/20 0.41
TTR P02766 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 2/20 0.41
ALB P02768 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
RECQL P46063 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9149322 0.84 PTGS1 (0.38) CYP3A4TSHRTDP1TRPA1TTR
SCHEMBL19655038 0.84 TRPA1 (0.38) CYP3A4TSHRTDP1TRPA1LCK
SCHEMBL8089211 0.78 TRPA1 (0.74) CYP3A4TSHRTDP1TRPA1LCK
SCHEMBL8089207 0.78 TRPA1 (0.74) CYP3A4TSHRTDP1TRPA1LCK
SCHEMBL5613166 0.78 APEX1 (0.45) TSHRTDP1ALDH1A1CA1CA2
SCHEMBL12004083 0.74 TP53 (0.39) TSHRTDP1ALDH1A1
SCHEMBL373244 0.74 ERN1 (0.52) CYP3A4TSHRTDP1TRPA1LCK
SCHEMBL31380876 0.73 TRPA1 (0.52) TRPA1LCKMEN1KMT2AALDH1A1
SCHEMBL2885475 0.73 TRPA1 (0.52) TRPA1LCKMEN1KMT2AALDH1A1
SCHEMBL665222 0.72 ALDH1A1 (0.44) CYP3A4TSHRTDP1TRPA1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2016464-B1 NEGATIVE PHOTORESIST COMPOSITIONS MERCK PATENT GMBH (DE) 2021-04-28 EP claimed
US-7601482-B2 Negative photoresist compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-10-13 US claimed
EP-2016464-A2 NEGATIVE PHOTORESIST COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2009-01-21 EP claimed
WO-2007110773-A2 NEGATIVE PHOTORESIST COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2007-10-04 WO claimed
US-20070231735-A1 Negative photoresist compositions MERCK PATENT GMBH (DE) 2007-10-04 US claimed
EP-4702010-A1 PHOTOACTIVE COMPOUNDS Merck Patent GmbH (DE) 2026-03-04 EP disclosed
WO-2024223739-A1 PHOTOACTIVE COMPOUNDS MERCK PATENT GMBH (DE) 2024-10-31 WO disclosed
CN-110032042-B Negative photoresist composition for laser ablation and method of use thereof 默克专利有限公司 2022-05-27 CN disclosed
CN-108139670-B Negative photoresist composition for laser ablation and method of use thereof 默克专利有限公司 2021-07-09 CN disclosed
EP-2016464-B1 NEGATIVE PHOTORESIST COMPOSITIONS MERCK PATENT GMBH (DE) 2021-04-28 EP disclosed
US-10705424-B2 Negative-working photoresist compositions for laser ablation and use thereof MERCK PATENT GMBH (DE) 2020-07-07 US disclosed
EP-3394674-B1 NEGATIVE-WORKING PHOTORESIST COMPOSITIONS FOR LASER ABLATION AND PROCESSES USING THEM AZ ELECTRONIC MAT LUXEMBOURG SARL (LU) 2020-05-06 EP disclosed
EP-0353339-A2 A process for the production of poly(3-mono or 3,5-disubstituted-4-Acetoxystryrenes), their copolymers and hydrolysis thereof HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-07 EP disclosed
US-4868257-A Process for the production of 3-mono or 3,5 disubstituted-4-acetoxystyrene, its polymerization HOECHST CELANESE CORPORATION (US) 1989-09-19 US disclosed
US-4868256-A Process for the production of 3-mono or 3,5-disubstituted-4-acetoxystyrene its polymerization, and hydrolysis HOECHST CELANESE (US) 1989-09-19 US disclosed
EP-0307752-A2 Poly(3-mono- and 3,5-disubstituted-4-acetoxystyrenes and 4-hydroxy-styrenes)and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-22 EP disclosed
EP-0307751-A2 3-mono- and 3,5-disubstituted-4-acetoxy and -4-hydroxystyrenes and process for their production HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-22 EP disclosed
EP-0082355-A2 Semipermeable membranes of modified polystyrene, process for their manufacture and their use ALIGENA AG (CH) 1983-06-29 EP disclosed
US-4075237-A Perfluorinated esters of fumaric acid and certain other ethylenically unsaturated poly-basic acid and soil repellant polymers thereof GEIGY CHEMICAL CORPORATION (US) 1978-02-21 US disclosed
US-3949136-A OIL REPELLENTS, WATERPROOFING TEXTILES CIBA-GEIGY AG (CH) 1976-04-06 US disclosed