⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383851 | 0.97 | OPRM1 (0.44) | — | |
| SCHEMBL7628906 | 0.97 | OPRM1 (0.44) | — | |
| SCHEMBL387477 | 0.92 | — | — | |
| SCHEMBL16782308 | 0.76 | OPRM1 (0.48) | — | |
| SCHEMBL29647839 | 0.76 | OPRM1 (0.48) | — | |
| SCHEMBL9438117 | 0.76 | OPRM1 (0.48) | — | |
| SCHEMBL387860 | 0.76 | LMNA (0.46) | — | |
| SCHEMBL1694582 | 0.76 | — | — | |
| SCHEMBL8082595 | 0.75 | LMNA (0.39) | — | |
| SCHEMBL8705831 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115626949-A | BET protein targeted degradation compound and preparation method and application thereof | 南京澳健生物制药有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-115612699-A | Copolymer membrane and enzymatic self-assembly synthesis method and application thereof at gas-liquid interface | 中国科学院天津工业生物技术研究所 | 2023-01-17 | — | — | CN | disclosed |
| CN-115612403-A | Self-assembly strong-adhesion copolymer film, film coating method and application | 中国科学院天津工业生物技术研究所 | 2023-01-17 | — | — | CN | disclosed |
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | disclosed |
| CN-115215867-A | FXIa inhibitor, pharmaceutical composition, preparation method and application thereof | 上海美悦生物科技发展有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-115003671-A | JNK inhibitors, pharmaceutical compositions and uses thereof | 武汉朗来科技发展有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-111995548-B | Preparation method of cyano tertiary amine | 河南省化工研究所有限责任公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-111793052-B | Benzoproline near-infrared fluorescent dye and preparation method and application thereof | 中国科学院理化技术研究所 | 2022-08-30 | — | — | CN | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-112467210-B | Lithium ion battery and preparation method thereof | 珠海冠宇电池股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| US-6964976-B2 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2005-11-15 | — | — | US | disclosed |
| US-20050043386-A1 | Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these | SANKYO COMPANY, LIMITED (JP) | 2005-02-24 | — | — | US | disclosed |
| EP-1471054-A1 | AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE | Sankyo Company, Limited (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-20040132784-A1 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-07-08 | — | — | US | disclosed |
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20030236297-A1 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |
| EP-1300405-A1 | AMINO ALCOHOL DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-09 | — | — | EP | disclosed |
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |