Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383851 | 1.00 | OPRM1 (0.44) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL386463 | 0.97 | — | — | |
| SCHEMBL387477 | 0.90 | — | — | |
| SCHEMBL29647839 | 0.79 | OPRM1 (0.48) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL16782308 | 0.79 | OPRM1 (0.48) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL9438117 | 0.79 | OPRM1 (0.48) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL8082595 | 0.78 | LMNA (0.39) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL1694200 | 0.77 | SPHK1 (0.48) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL1694745 | 0.77 | SPHK1 (0.48) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL25252646 | 0.75 | TSHR (0.48) | OPRM1SPHK1LMNADNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420452-B1 | POLYURETHANES WITH EXTENDERS | AORTECH BIOMATERIALS PTY LTD (AU) | 2002-07-16 | — | — | US | claimed |